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Epigenome-wide association studies: potential insights into human disease

Epigenome-wide association studies: potential insights into human disease
Epigenome-wide association studies: potential insights into human disease
The burden on human health due to common diseases, such as the metabolic syndrome, cardiovascular and inflammatory disorders is extreme. With increasingly longer lived populations, the morbidity of these chronic conditions leads to vast physical, psychological and economic cost. In order to further understand the pathogenicity of these complex diseases, the intertwined influence of environmental factors and polygenic susceptibility needs to be unravelled. This may at first seem an insurmountably difficult task but progress has been made in recent years
287-317
Springer
Bell, Christopher G.
44982df7-0746-4cdb-bed1-0bdfe68f1a64
Naumova, Anna K.
Greenwood, Celia M.T.
Bell, Christopher G.
44982df7-0746-4cdb-bed1-0bdfe68f1a64
Naumova, Anna K.
Greenwood, Celia M.T.

Bell, Christopher G. (2013) Epigenome-wide association studies: potential insights into human disease. In, Naumova, Anna K. and Greenwood, Celia M.T. (eds.) Epigenetics and Complex Traits. Springer, pp. 287-317. (doi:10.1007/978-1-4614-8078-5_13).

Record type: Book Section

Abstract

The burden on human health due to common diseases, such as the metabolic syndrome, cardiovascular and inflammatory disorders is extreme. With increasingly longer lived populations, the morbidity of these chronic conditions leads to vast physical, psychological and economic cost. In order to further understand the pathogenicity of these complex diseases, the intertwined influence of environmental factors and polygenic susceptibility needs to be unravelled. This may at first seem an insurmountably difficult task but progress has been made in recent years

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More information

Published date: 9 August 2013
Organisations: Human Development & Health, Centre for Biological Sciences, MRC Life-Course Epidemiology Unit

Identifiers

Local EPrints ID: 401016
URI: https://eprints.soton.ac.uk/id/eprint/401016
PURE UUID: 94607eae-6977-45ae-8f66-bf334c618e0b
ORCID for Christopher G. Bell: ORCID iD orcid.org/0000-0003-4601-1242

Catalogue record

Date deposited: 03 Oct 2016 12:49
Last modified: 11 Apr 2019 00:30

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