The University of Southampton
University of Southampton Institutional Repository

Characterizing the ADHD phenotype for genetic studies

Stevenson, Jim, Asherson, Phil, Hay, David, Levy, Florence, Swanson, Jim, Thapar, Anita and Willcutt, Erik (2005) Characterizing the ADHD phenotype for genetic studies Developmental Science, 8, (2), pp. 115-121. (doi:10.1111/j.1467-7687.2005.00398.x).

Record type: Article

Abstract

The genetic study of ADHD has made considerable progress. Further developments in the field will be reliant in part on identifying the most appropriate phenotypes for genetic analysis. The use of both categorical and dimensional measures of symptoms related to ADHD has been productive. The use of multiple reporters is a valuable feature of the characterization of psychopathology in children. It is argued that the use of aggregated measures to characterize the ADHD phenotype, particularly to establish its pervasiveness, is desirable. The recognition of the multiple comorbidities of ADHD can help to isolate more specific genetic influences. In relation to both reading disability and conduct disorder there is evidence that genes may be involved in the comorbid condition that are different from pure ADHD. To date, progress with the investigation of endophenotypes for ADHD has been disappointing. It is suggested that extending such studies beyond cognitive underpinnings to include physiological and metabolic markers might facilitate progress.

Full text not available from this repository.

More information

Published date: 2005

Identifiers

Local EPrints ID: 40128
URI: http://eprints.soton.ac.uk/id/eprint/40128
PURE UUID: 943151f7-33f0-4c2e-a367-4cc47cc94fec

Catalogue record

Date deposited: 03 Jul 2006
Last modified: 17 Jul 2017 15:35

Export record

Altmetrics

Contributors

Author: Jim Stevenson
Author: Phil Asherson
Author: David Hay
Author: Florence Levy
Author: Jim Swanson
Author: Anita Thapar
Author: Erik Willcutt

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×