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Efficacy of a virtual assistance-based lifestyle intervention in reducing risk factors for Type 2 diabetes in young employees in the information technology industry in India: LIMIT, a randomized controlled trial

Efficacy of a virtual assistance-based lifestyle intervention in reducing risk factors for Type 2 diabetes in young employees in the information technology industry in India: LIMIT, a randomized controlled trial
Efficacy of a virtual assistance-based lifestyle intervention in reducing risk factors for Type 2 diabetes in young employees in the information technology industry in India: LIMIT, a randomized controlled trial
Aims: To investigate a virtual assistance-based lifestyle intervention to reduce risk factors for Type 2 diabetes in young employees in the information technology industry in India.

Methods: LIMIT (Lifestyle Modification in Information Technology) was a parallel-group, partially blinded, randomized controlled trial. Employees in the information technology industry with ?3 risk factors (family history of cardiometabolic disease, overweight/obesity, high blood pressure, impaired fasting glucose, hypertriglyceridaemia, high LDL cholesterol and low HDL cholesterol) from two industries were randomized to a control or an intervention (1:1) group. After initial lifestyle advice, the intervention group additionally received reinforcement through mobile phone messages (three per week) and e-mails (two per week) for 1 year. The primary outcome was change in prevalence of overweight/obesity, analysed by intention to treat.

Results: Of 437 employees screened (mean age 36.2 ± 9.3 years; 74.8% men), 265 (61.0%) were eligible and randomized into control (n=132) or intervention (n=133) group. After 1 year, the prevalence of overweight/obesity reduced by 6.0% in the intervention group and increased by 6.8% in the control group (risk difference 11.2%; 95% CI 1.2–21.1; P=0.042). There were also significant improvements in lifestyle measurements, waist circumference, and total and LDL cholesterol in the intervention group.

The number-needed-to-treat to prevent one case of overweight/obesity in 1 year was 9 (95% CI 5–82), with an incremental cost of INR10665 (£112.30) per case treated/prevented. A total of 98% of participants found the intervention acceptable.

Conclusions: A virtual assistance-based lifestyle intervention was effective, cost-effective and acceptable in reducing risk factors for diabetes in young employees in the information technology industry, and is potentially scalable
0742-3071
563-568
Limaye, T.
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Kumaran, K.
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Joglekar, C.
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Bhat, Dattatray
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Kulkarni, R.
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Nanivadekar, A.
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Yajnik, C.
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Limaye, T.
f67bcb20-fe1c-4bfa-bb92-94d94e96697c
Kumaran, K.
de6f872c-7339-4a52-be84-e3bbae707744
Joglekar, C.
70e3e271-1071-46f2-9986-790d7e8fea6b
Bhat, Dattatray
2dcfc738-f249-4ee7-a61c-c91c964c9009
Kulkarni, R.
12aeab9a-b885-4e11-80f1-9456c4a6e419
Nanivadekar, A.
bdc8c344-ddbe-46ed-b8cb-bff85f07efdd
Yajnik, C.
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Limaye, T., Kumaran, K., Joglekar, C., Bhat, Dattatray, Kulkarni, R., Nanivadekar, A. and Yajnik, C. (2017) Efficacy of a virtual assistance-based lifestyle intervention in reducing risk factors for Type 2 diabetes in young employees in the information technology industry in India: LIMIT, a randomized controlled trial. Diabetic Medicine, 34 (4), 563-568. (doi:10.1111/dme.13258).

Record type: Article

Abstract

Aims: To investigate a virtual assistance-based lifestyle intervention to reduce risk factors for Type 2 diabetes in young employees in the information technology industry in India.

Methods: LIMIT (Lifestyle Modification in Information Technology) was a parallel-group, partially blinded, randomized controlled trial. Employees in the information technology industry with ?3 risk factors (family history of cardiometabolic disease, overweight/obesity, high blood pressure, impaired fasting glucose, hypertriglyceridaemia, high LDL cholesterol and low HDL cholesterol) from two industries were randomized to a control or an intervention (1:1) group. After initial lifestyle advice, the intervention group additionally received reinforcement through mobile phone messages (three per week) and e-mails (two per week) for 1 year. The primary outcome was change in prevalence of overweight/obesity, analysed by intention to treat.

Results: Of 437 employees screened (mean age 36.2 ± 9.3 years; 74.8% men), 265 (61.0%) were eligible and randomized into control (n=132) or intervention (n=133) group. After 1 year, the prevalence of overweight/obesity reduced by 6.0% in the intervention group and increased by 6.8% in the control group (risk difference 11.2%; 95% CI 1.2–21.1; P=0.042). There were also significant improvements in lifestyle measurements, waist circumference, and total and LDL cholesterol in the intervention group.

The number-needed-to-treat to prevent one case of overweight/obesity in 1 year was 9 (95% CI 5–82), with an incremental cost of INR10665 (£112.30) per case treated/prevented. A total of 98% of participants found the intervention acceptable.

Conclusions: A virtual assistance-based lifestyle intervention was effective, cost-effective and acceptable in reducing risk factors for diabetes in young employees in the information technology industry, and is potentially scalable

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Accepted/In Press date: 31 August 2016
e-pub ahead of print date: 6 October 2016
Published date: April 2017
Organisations: Faculty of Medicine

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Local EPrints ID: 401531
URI: http://eprints.soton.ac.uk/id/eprint/401531
ISSN: 0742-3071
PURE UUID: fb71c70c-6ed9-4ed1-9026-8a5a9befc010

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Date deposited: 18 Oct 2016 12:30
Last modified: 07 Oct 2020 04:03

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Contributors

Author: T. Limaye
Author: K. Kumaran
Author: C. Joglekar
Author: Dattatray Bhat
Author: R. Kulkarni
Author: A. Nanivadekar
Author: C. Yajnik

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