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International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue

International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue
International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue
In this narrative review we studied the association of risk factors for CKD and CKD prevalence at an ecological level and describe potential reasons for international differences in estimated CKD prevalence across European countries. We found substantial variation in risk factors for CKD such as in the prevalence of diabetes mellitus, obesity, raised blood pressure, physical inactivity, and current smoking, and in salt intake per day. In general, the countries with a higher CKD prevalence also had a higher average score on CKD risk factors, and vice versa. There was no association between cardiovascular mortality rates and CKD prevalence. In countries with a high CKD prevalence the prevention of non-communicable diseases may be considered important and therefore all five national response systems (e.g. an operational national policy, strategy or action plan to reduce physical inactivity and/or promote physical activity) have been implemented. Furthermore, both the heterogeneity in study methods to assess CKD prevalence as well as the international differences in the implementation of lifestyle measures will contribute to the observed variation in CKD prevalence. A robust public health approach to reduce risk factors in order to prevent CKD and reduce CKD progression risk is needed and will have co-benefits for other non-communicable diseases.
0931-0509
1-18
Stel, Vianda S.
78fec1f1-91ea-4a90-8eff-07f7e1d6427f
Bruck, Katharina
64000242-de07-4ecb-a391-d7e9da53cbf1
Fraser, Simon
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Zoccali, Carmine
6142b045-95d1-435d-b165-61c1a0c27619
Massy, Ziad A.
66f49e03-d6da-4451-bfe1-734f3e68a86a
Jager, Kitty J.
0dacf760-b370-43b1-bb6e-1b6b645826ab
Stel, Vianda S.
78fec1f1-91ea-4a90-8eff-07f7e1d6427f
Bruck, Katharina
64000242-de07-4ecb-a391-d7e9da53cbf1
Fraser, Simon
135884b6-8737-4e8a-a98c-5d803ac7a2dc
Zoccali, Carmine
6142b045-95d1-435d-b165-61c1a0c27619
Massy, Ziad A.
66f49e03-d6da-4451-bfe1-734f3e68a86a
Jager, Kitty J.
0dacf760-b370-43b1-bb6e-1b6b645826ab

Stel, Vianda S., Bruck, Katharina, Fraser, Simon, Zoccali, Carmine, Massy, Ziad A. and Jager, Kitty J. (2017) International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue. Nephrology, Dialysis, Transplantation, 1-18. (doi:10.1093/ndt/gfw420).

Record type: Article

Abstract

In this narrative review we studied the association of risk factors for CKD and CKD prevalence at an ecological level and describe potential reasons for international differences in estimated CKD prevalence across European countries. We found substantial variation in risk factors for CKD such as in the prevalence of diabetes mellitus, obesity, raised blood pressure, physical inactivity, and current smoking, and in salt intake per day. In general, the countries with a higher CKD prevalence also had a higher average score on CKD risk factors, and vice versa. There was no association between cardiovascular mortality rates and CKD prevalence. In countries with a high CKD prevalence the prevention of non-communicable diseases may be considered important and therefore all five national response systems (e.g. an operational national policy, strategy or action plan to reduce physical inactivity and/or promote physical activity) have been implemented. Furthermore, both the heterogeneity in study methods to assess CKD prevalence as well as the international differences in the implementation of lifestyle measures will contribute to the observed variation in CKD prevalence. A robust public health approach to reduce risk factors in order to prevent CKD and reduce CKD progression risk is needed and will have co-benefits for other non-communicable diseases.

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Stel_CKD_prevalence_review_paper_20161810_ACCEPTED.pdf - Accepted Manuscript
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More information

Accepted/In Press date: 8 November 2016
e-pub ahead of print date: 16 February 2017
Published date: 16 February 2017
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 402567
URI: http://eprints.soton.ac.uk/id/eprint/402567
ISSN: 0931-0509
PURE UUID: 1064a6cf-fe5c-42d0-962e-0f129f99fe55
ORCID for Simon Fraser: ORCID iD orcid.org/0000-0002-4172-4406

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Date deposited: 11 Nov 2016 15:14
Last modified: 15 Mar 2024 06:03

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Contributors

Author: Vianda S. Stel
Author: Katharina Bruck
Author: Simon Fraser ORCID iD
Author: Carmine Zoccali
Author: Ziad A. Massy
Author: Kitty J. Jager

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