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A new benzodiazepine molecule and its interactions with diorganotin(IV)chlorides

A new benzodiazepine molecule and its interactions with diorganotin(IV)chlorides
A new benzodiazepine molecule and its interactions with diorganotin(IV)chlorides
2-Methyl-2,4-di-thiophen-2?,2?-yl-2,3-dihydro-1H-benzo[b][1,4]diazepine (L) has been synthesized through condensation of phenylene-1,2-diamine and 2-acetylthiophene, and its reactions with dialkyltin(IV)dichlorides have been studied. Two salts formulated as (LH)[R2SnCl3] (R = Et, 1; R = Me, 2) have been isolated. L and 1 were structurally characterized. The conformation of the benzodiazepine L, changes in 1 due to H-bonds formation. [Et2SnCl3]- is one of the rare examples of five coordinated tin(IV) species and has distorted trigonal bipyramidal geometry. H-bonding interactions, in 1, lead to the formation of supramolecular helices.
0022-2860
473-479
Garoufis, Achilleas
8a7ede74-724e-4570-bce7-089d8f376779
Kitos, Alexandros A.
d6ba8e59-0254-49da-a066-aa1d67c1ddc3
Lymperopoulou, Smaragda
8a5b1800-8ead-44f6-91ce-5ec6e0f12abd
Nastopoulos, Vasileios
4f7976c0-e25f-4816-af04-63c496c142f6
Plakatouras, John C.
60eeb53f-491a-44e9-ac12-33b61abb2635
Ypsilantis, Konstantinos
a3a77476-f6cd-492a-af92-cdea3daf9d32
Garoufis, Achilleas
8a7ede74-724e-4570-bce7-089d8f376779
Kitos, Alexandros A.
d6ba8e59-0254-49da-a066-aa1d67c1ddc3
Lymperopoulou, Smaragda
8a5b1800-8ead-44f6-91ce-5ec6e0f12abd
Nastopoulos, Vasileios
4f7976c0-e25f-4816-af04-63c496c142f6
Plakatouras, John C.
60eeb53f-491a-44e9-ac12-33b61abb2635
Ypsilantis, Konstantinos
a3a77476-f6cd-492a-af92-cdea3daf9d32

Garoufis, Achilleas, Kitos, Alexandros A., Lymperopoulou, Smaragda, Nastopoulos, Vasileios, Plakatouras, John C. and Ypsilantis, Konstantinos (2015) A new benzodiazepine molecule and its interactions with diorganotin(IV)chlorides. Journal of Molecular Structure, 1079, 473-479. (doi:10.1016/j.molstruc.2014.09.055).

Record type: Article

Abstract

2-Methyl-2,4-di-thiophen-2?,2?-yl-2,3-dihydro-1H-benzo[b][1,4]diazepine (L) has been synthesized through condensation of phenylene-1,2-diamine and 2-acetylthiophene, and its reactions with dialkyltin(IV)dichlorides have been studied. Two salts formulated as (LH)[R2SnCl3] (R = Et, 1; R = Me, 2) have been isolated. L and 1 were structurally characterized. The conformation of the benzodiazepine L, changes in 1 due to H-bonds formation. [Et2SnCl3]- is one of the rare examples of five coordinated tin(IV) species and has distorted trigonal bipyramidal geometry. H-bonding interactions, in 1, lead to the formation of supramolecular helices.

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More information

Accepted/In Press date: 19 September 2014
e-pub ahead of print date: 12 October 2014
Published date: 5 January 2015
Organisations: Organic Chemistry: SCF

Identifiers

Local EPrints ID: 403243
URI: http://eprints.soton.ac.uk/id/eprint/403243
ISSN: 0022-2860
PURE UUID: e229a275-1e0f-4744-aa0c-cfd3d16da1b4
ORCID for Smaragda Lymperopoulou: ORCID iD orcid.org/0000-0001-7871-4159

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Date deposited: 29 Nov 2016 10:09
Last modified: 15 Mar 2024 03:37

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Contributors

Author: Achilleas Garoufis
Author: Alexandros A. Kitos
Author: Smaragda Lymperopoulou ORCID iD
Author: Vasileios Nastopoulos
Author: John C. Plakatouras
Author: Konstantinos Ypsilantis

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