Hybrid diphenylalkyne-dipeptide oligomers induce multistrand B-sheet formation

Ross, Jonathan E., Knipe, Peter C., Thompson, Sam and Hamilton, Andrew D. (2015) Hybrid diphenylalkyne-dipeptide oligomers induce multistrand B-sheet formation. Chemistry - A European Journal, 21 (39), 13518-13521. (doi:10.1002/chem.201502690).

Record type: Article

Abstract

Functionalized diphenylalkynes provide a template for the presentation of protein-like surfaces composed of multistrand ?-sheets. The conformational properties of three-, four-, and seven-stranded systems have been investigated in the solid- and solution-state. This class of molecule may be suitable for the mediation of therapeutically relevant protein–protein interactions.

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e-pub ahead of print date: 11 August 2015

Published date: 21 September 2015

Organisations: Chemistry

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Local EPrints ID: 403572

URI: http://eprints.soton.ac.uk/id/eprint/403572

DOI: doi:10.1002/chem.201502690

ISSN: 0947-6539

PURE UUID: 5df22c60-3154-4936-a44e-7762b7d92d17

ORCID for Sam Thompson:

orcid.org/0000-0001-6267-5693

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Date deposited: 07 Dec 2016 09:41

Last modified: 15 Mar 2024 03:54

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Contributors

Author: Jonathan E. Ross

Author: Peter C. Knipe

Author: Sam Thompson

Author: Andrew D. Hamilton

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