Improved traditional phytomedicines in current use for the clinical treatment of malaria
Improved traditional phytomedicines in current use for the clinical treatment of malaria
Phytomedicines and “green pharmacies” are promoted by some NGOs and governments as part of their efforts to control malaria. “Improved traditional medicines” (ITMs) are standardised as regards preparation and dose, although not always according to the concentration of active compounds. A systematic literature search revealed that six such phytomedicines are currently government-approved in at least one country and used on a relatively large scale nationally or internationally: Artemisia annua L. (Asteraceae), Cinchona bark (Rubiaceae), Cryptolepis sanguinolenta (Lindl.) Schltr. (Apocynaceae), “Ayush-64”, “Malarial-5” and Cochlospermum planchonii Hook. f. ex Planch. (Bixaceae). One further ITM has been developed and is in the process of being approved: Argemone mexicana decoction. Their development, phytochemistry, pharmacology, and clinical trials are reviewed, as well as priorities for future research.
662-671
Willcox, Merlin
dad5b622-9ac2-417d-9b2e-aad41b64ffea
2011
Willcox, Merlin
dad5b622-9ac2-417d-9b2e-aad41b64ffea
Willcox, Merlin
(2011)
Improved traditional phytomedicines in current use for the clinical treatment of malaria.
Planta Medica, 77 (6), .
(doi:10.1055/s-0030-1250548).
Abstract
Phytomedicines and “green pharmacies” are promoted by some NGOs and governments as part of their efforts to control malaria. “Improved traditional medicines” (ITMs) are standardised as regards preparation and dose, although not always according to the concentration of active compounds. A systematic literature search revealed that six such phytomedicines are currently government-approved in at least one country and used on a relatively large scale nationally or internationally: Artemisia annua L. (Asteraceae), Cinchona bark (Rubiaceae), Cryptolepis sanguinolenta (Lindl.) Schltr. (Apocynaceae), “Ayush-64”, “Malarial-5” and Cochlospermum planchonii Hook. f. ex Planch. (Bixaceae). One further ITM has been developed and is in the process of being approved: Argemone mexicana decoction. Their development, phytochemistry, pharmacology, and clinical trials are reviewed, as well as priorities for future research.
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Published date: 2011
Organisations:
Primary Care & Population Sciences
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Local EPrints ID: 403767
URI: http://eprints.soton.ac.uk/id/eprint/403767
ISSN: 0032-0943
PURE UUID: 536e3e28-bb9b-4fa0-99f2-3ddeb6d39b05
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Date deposited: 09 Dec 2016 15:32
Last modified: 15 Mar 2024 03:57
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