Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar
Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar
The clinical efficacy of chloroquine was assessed in the Primary Health Centre of Ankazobe, Central Highlands of Madagascar. This study shows an increase in the level of chloroquine resistance with the appearance of early treatment failures and RIII resistance. Furthermore, the prevalence of clinical treatment failures is approaching the level of 25%, at which WHO recommends a change of first-line drug.
311-314
Willcox, M.L.
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Rakotondrazafy, E.
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Andriamanalimanana, R.
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Andrianasolo, D.
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Rasoanaivo, P.
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2004
Willcox, M.L.
d6b13eb3-f12d-495a-8809-32a1acccf7cf
Rakotondrazafy, E.
be6e5761-395b-4b9b-a4be-515b65aec76d
Andriamanalimanana, R.
c4088adf-3356-41bb-93c2-358e14ac5807
Andrianasolo, D.
222f768a-9ef9-4abb-a123-e64d208c8068
Rasoanaivo, P.
9f56ee49-4041-49c0-81d0-e47297819262
Willcox, M.L., Rakotondrazafy, E., Andriamanalimanana, R., Andrianasolo, D. and Rasoanaivo, P.
(2004)
Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 98 (5), .
(doi:10.1016/j.trstmh.2003.10.002).
Abstract
The clinical efficacy of chloroquine was assessed in the Primary Health Centre of Ankazobe, Central Highlands of Madagascar. This study shows an increase in the level of chloroquine resistance with the appearance of early treatment failures and RIII resistance. Furthermore, the prevalence of clinical treatment failures is approaching the level of 25%, at which WHO recommends a change of first-line drug.
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Accepted/In Press date: 13 October 2003
Published date: 2004
Organisations:
Primary Care & Population Sciences
Identifiers
Local EPrints ID: 403936
URI: http://eprints.soton.ac.uk/id/eprint/403936
ISSN: 0035-9203
PURE UUID: bd195db4-e1bd-4843-aaaa-01eb772861f0
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Date deposited: 15 Dec 2016 15:13
Last modified: 15 Mar 2024 03:54
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Contributors
Author:
M.L. Willcox
Author:
E. Rakotondrazafy
Author:
R. Andriamanalimanana
Author:
D. Andrianasolo
Author:
P. Rasoanaivo
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