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Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar

Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar
Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar
The clinical efficacy of chloroquine was assessed in the Primary Health Centre of Ankazobe, Central Highlands of Madagascar. This study shows an increase in the level of chloroquine resistance with the appearance of early treatment failures and RIII resistance. Furthermore, the prevalence of clinical treatment failures is approaching the level of 25%, at which WHO recommends a change of first-line drug.
0035-9203
311-314
Willcox, M.L.
d6b13eb3-f12d-495a-8809-32a1acccf7cf
Rakotondrazafy, E.
be6e5761-395b-4b9b-a4be-515b65aec76d
Andriamanalimanana, R.
c4088adf-3356-41bb-93c2-358e14ac5807
Andrianasolo, D.
222f768a-9ef9-4abb-a123-e64d208c8068
Rasoanaivo, P.
9f56ee49-4041-49c0-81d0-e47297819262
Willcox, M.L.
d6b13eb3-f12d-495a-8809-32a1acccf7cf
Rakotondrazafy, E.
be6e5761-395b-4b9b-a4be-515b65aec76d
Andriamanalimanana, R.
c4088adf-3356-41bb-93c2-358e14ac5807
Andrianasolo, D.
222f768a-9ef9-4abb-a123-e64d208c8068
Rasoanaivo, P.
9f56ee49-4041-49c0-81d0-e47297819262

Willcox, M.L., Rakotondrazafy, E., Andriamanalimanana, R., Andrianasolo, D. and Rasoanaivo, P. (2004) Decreasing clinical efficacy of chloroquine in Ankazobe, central highlands of Madagascar. Transactions of the Royal Society of Tropical Medicine and Hygiene, 98 (5), 311-314. (doi:10.1016/j.trstmh.2003.10.002).

Record type: Article

Abstract

The clinical efficacy of chloroquine was assessed in the Primary Health Centre of Ankazobe, Central Highlands of Madagascar. This study shows an increase in the level of chloroquine resistance with the appearance of early treatment failures and RIII resistance. Furthermore, the prevalence of clinical treatment failures is approaching the level of 25%, at which WHO recommends a change of first-line drug.

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More information

Accepted/In Press date: 13 October 2003
Published date: 2004
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 403936
URI: https://eprints.soton.ac.uk/id/eprint/403936
ISSN: 0035-9203
PURE UUID: bd195db4-e1bd-4843-aaaa-01eb772861f0

Catalogue record

Date deposited: 15 Dec 2016 15:13
Last modified: 15 Jul 2019 19:49

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Contributors

Author: M.L. Willcox
Author: E. Rakotondrazafy
Author: R. Andriamanalimanana
Author: D. Andrianasolo
Author: P. Rasoanaivo

University divisions

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