The University of Southampton
University of Southampton Institutional Repository

A core outcome set for evaluating self-management interventions in people with comorbid diabetes and severe mental illness: study protocol for a modified Delphi study and systematic review

A core outcome set for evaluating self-management interventions in people with comorbid diabetes and severe mental illness: study protocol for a modified Delphi study and systematic review
A core outcome set for evaluating self-management interventions in people with comorbid diabetes and severe mental illness: study protocol for a modified Delphi study and systematic review
Background: People with diabetes and comorbid severe mental illness (SMI) form a growing population at risk of increased mortality and morbidity compared to those with diabetes or SMI alone. There is increasing interest in interventions that target diabetes in SMI in order to help improve physical health and reduce the associated health inequalities. However, there is a lack of consensus about which outcomes are important for this comorbid population, with trials differing in their focus on physical and mental health. A core outcome set which includes outcomes across both conditions that are relevant to patients and other key stakeholders is needed.

Methods: This study protocol describes methods to develop a core outcome set for use in effectiveness trials of self-management interventions for adults with comorbid type 2 diabetes and SMI. We will use a modified Delphi method to identify, rank and agree core outcomes. This will comprise a two round online survey and multi-stakeholder workshops involving patients and carers, health and social care professionals, healthcare commissioners, and other experts (e.g. academic researchers and third sector organisations). We will also select appropriate measurement tools for each outcome in the proposed core set and identify gaps in measures, where these exist.

Discussion: The proposed core outcome set will provide clear guidance about what outcomes should be measured, as a minimum, in trials of interventions for people with coexisting type 2 diabetes and SMI, and improve future synthesis of trial evidence in this area. We will also explore the challenges of using online Delphi methods for this hard-to-reach population, and examine differences in opinion about which outcomes matter to diverse stakeholder groups.

COMET registration: http://www.comet-initiative.org/studies/details/911 (registered 01 July 2016).
Keywords: psychosis, severe mental illness, schizophrenia, bipolar disorder, diabetes, self-management, core outcome set, co-morbidity, complex interventions
1745-6215
1-26
Taylor, J.
a98e31be-d5c2-4442-a3e9-472af9399f52
Bohnke, J.R.
6cc30d7e-37ff-4af7-b2c7-46b93e5ee742
Wright, J.
cc93f054-d4d6-45bb-b88e-adc0c6545ac3
Kellar, I.
abe4a131-b468-4522-9988-3401ed0bb9cc
Alderson, S.
00ee9859-a11f-4040-a963-d88d4ae2740d
Hughes, T.
e7ab9d6a-57d7-45d3-9a1b-bc00df50432e
Holt, R.I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393
Siddiqi, N.
8ded6f93-6de8-4375-80f6-fc516eea35b1
Taylor, J.
a98e31be-d5c2-4442-a3e9-472af9399f52
Bohnke, J.R.
6cc30d7e-37ff-4af7-b2c7-46b93e5ee742
Wright, J.
cc93f054-d4d6-45bb-b88e-adc0c6545ac3
Kellar, I.
abe4a131-b468-4522-9988-3401ed0bb9cc
Alderson, S.
00ee9859-a11f-4040-a963-d88d4ae2740d
Hughes, T.
e7ab9d6a-57d7-45d3-9a1b-bc00df50432e
Holt, R.I.G.
d54202e1-fcf6-4a17-a320-9f32d7024393
Siddiqi, N.
8ded6f93-6de8-4375-80f6-fc516eea35b1

Taylor, J., Bohnke, J.R., Wright, J., Kellar, I., Alderson, S., Hughes, T., Holt, R.I.G. and Siddiqi, N. (2017) A core outcome set for evaluating self-management interventions in people with comorbid diabetes and severe mental illness: study protocol for a modified Delphi study and systematic review. Trials, 1-26. (In Press)

Record type: Article

Abstract

Background: People with diabetes and comorbid severe mental illness (SMI) form a growing population at risk of increased mortality and morbidity compared to those with diabetes or SMI alone. There is increasing interest in interventions that target diabetes in SMI in order to help improve physical health and reduce the associated health inequalities. However, there is a lack of consensus about which outcomes are important for this comorbid population, with trials differing in their focus on physical and mental health. A core outcome set which includes outcomes across both conditions that are relevant to patients and other key stakeholders is needed.

Methods: This study protocol describes methods to develop a core outcome set for use in effectiveness trials of self-management interventions for adults with comorbid type 2 diabetes and SMI. We will use a modified Delphi method to identify, rank and agree core outcomes. This will comprise a two round online survey and multi-stakeholder workshops involving patients and carers, health and social care professionals, healthcare commissioners, and other experts (e.g. academic researchers and third sector organisations). We will also select appropriate measurement tools for each outcome in the proposed core set and identify gaps in measures, where these exist.

Discussion: The proposed core outcome set will provide clear guidance about what outcomes should be measured, as a minimum, in trials of interventions for people with coexisting type 2 diabetes and SMI, and improve future synthesis of trial evidence in this area. We will also explore the challenges of using online Delphi methods for this hard-to-reach population, and examine differences in opinion about which outcomes matter to diverse stakeholder groups.

COMET registration: http://www.comet-initiative.org/studies/details/911 (registered 01 July 2016).
Keywords: psychosis, severe mental illness, schizophrenia, bipolar disorder, diabetes, self-management, core outcome set, co-morbidity, complex interventions

Text
__userfiles.soton.ac.uk_Users_nl2_mydesktop_Deposits_One off_Taylor COS study protocol manuscript v3 141016 CLEAN.docx - Accepted Manuscript
Download (178kB)

More information

Accepted/In Press date: 14 January 2017
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 404947
URI: http://eprints.soton.ac.uk/id/eprint/404947
ISSN: 1745-6215
PURE UUID: 8bdc5e37-6411-4963-b46e-865f56a003f0
ORCID for R.I.G. Holt: ORCID iD orcid.org/0000-0001-8911-6744

Catalogue record

Date deposited: 25 Jan 2017 11:12
Last modified: 18 Feb 2021 16:56

Export record

Contributors

Author: J. Taylor
Author: J.R. Bohnke
Author: J. Wright
Author: I. Kellar
Author: S. Alderson
Author: T. Hughes
Author: R.I.G. Holt ORCID iD
Author: N. Siddiqi

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×