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A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis

A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis
A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis
Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids. Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.
0036-8075
744-747
Kreuger, Julia
c0550aaf-975b-4240-806d-a0fa376640c3
Thomas, Colwyn M.
1624aef2-b325-4ca4-8192-5696d179ff55
Golstein, Catherine
3b9d5f0c-400d-4e7c-b581-34b18360f50f
Dixon, Mark S.
9debc1f1-fae6-4ed4-a9b5-f080577c15fc
Smoker, Matthew
84097b62-55b3-4d67-b9d0-068c8138e5f0
Tang, Saijun
66ee2d04-c4df-4193-96b5-2289f0e3100f
Mulder, Lonneke
ab49537c-96bd-4c15-baaa-114c12b6e744
Jones, Jonathan D.G.
e7527157-ca3a-4d5d-a678-33e226d1de09
Kreuger, Julia
c0550aaf-975b-4240-806d-a0fa376640c3
Thomas, Colwyn M.
1624aef2-b325-4ca4-8192-5696d179ff55
Golstein, Catherine
3b9d5f0c-400d-4e7c-b581-34b18360f50f
Dixon, Mark S.
9debc1f1-fae6-4ed4-a9b5-f080577c15fc
Smoker, Matthew
84097b62-55b3-4d67-b9d0-068c8138e5f0
Tang, Saijun
66ee2d04-c4df-4193-96b5-2289f0e3100f
Mulder, Lonneke
ab49537c-96bd-4c15-baaa-114c12b6e744
Jones, Jonathan D.G.
e7527157-ca3a-4d5d-a678-33e226d1de09

Kreuger, Julia, Thomas, Colwyn M., Golstein, Catherine, Dixon, Mark S., Smoker, Matthew, Tang, Saijun, Mulder, Lonneke and Jones, Jonathan D.G. (2002) A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis. Science, 296 (5568), 744-747. (doi:10.1126/science.1069288).

Record type: Article

Abstract

Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids. Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.

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Published date: 2002

Identifiers

Local EPrints ID: 40510
URI: http://eprints.soton.ac.uk/id/eprint/40510
ISSN: 0036-8075
PURE UUID: cb4ed8cf-56d4-4c3a-90da-128edcee6e50

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Date deposited: 04 Jul 2006
Last modified: 15 Mar 2024 08:20

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Contributors

Author: Julia Kreuger
Author: Colwyn M. Thomas
Author: Catherine Golstein
Author: Mark S. Dixon
Author: Matthew Smoker
Author: Saijun Tang
Author: Lonneke Mulder
Author: Jonathan D.G. Jones

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