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A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis

Kreuger, Julia, Thomas, Colwyn M., Golstein, Catherine, Dixon, Mark S., Smoker, Matthew, Tang, Saijun, Mulder, Lonneke and Jones, Jonathan D.G. (2002) A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis Science, 296, (5568), pp. 744-747. (doi:10.1126/science.1069288).

Record type: Article


Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids. Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.

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Published date: 2002


Local EPrints ID: 40510
ISSN: 0036-8075
PURE UUID: cb4ed8cf-56d4-4c3a-90da-128edcee6e50

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Date deposited: 04 Jul 2006
Last modified: 17 Jul 2017 15:34

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Author: Julia Kreuger
Author: Colwyn M. Thomas
Author: Catherine Golstein
Author: Mark S. Dixon
Author: Matthew Smoker
Author: Saijun Tang
Author: Lonneke Mulder
Author: Jonathan D.G. Jones

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