The University of Southampton
University of Southampton Institutional Repository

Risk assessment of malaria in land border regions of China in the context of malaria elimination

Risk assessment of malaria in land border regions of China in the context of malaria elimination
Risk assessment of malaria in land border regions of China in the context of malaria elimination
BACKGROUND:Cross-border malaria transmission poses a challenge for countries to achieve and maintain malaria elimination. Because of a dramatic increase of cross-border population movement between China and 14 neighbouring countries, the malaria epidemic risk in China's land border regions needs to be understood.

METHODS: In this study, individual case-based epidemiological data on malaria in the 136 counties of China with international land borders, from 2011 to 2014, were extracted from the National Infectious Disease Information System. The Plasmodium species, seasonality, spatiotemporal distribution and changing features of imported and indigenous cases were analysed using descriptive spatial and temporal methods.

RESULTS:A total of 1948 malaria cases were reported, with 1406 (72.2%) imported cases and 542 (27.8%) indigenous cases. Plasmodium vivax is the predominant species, with 1536 malaria cases occurrence (78.9%), following by Plasmodium falciparum (361 cases, 18.5%), and the others (51 cases, 2.6%). The magnitude and geographic distribution of malaria in land border counties shrunk sharply during the elimination period. Imported malaria cases were with a peak of 546 cases in 2011, decreasing yearly in the following years. The number of counties with imported cases decreased from 28 counties in 2011 to 26 counties in 2014. Indigenous malaria cases presented a markedly decreasing trend, with 319 indigenous cases in 2011 reducing to only 33 indigenous cases in 2014. The number of counties with indigenous cases reduced from 26 counties in 2011 to 10 counties in 2014. However, several bordering counties of Yunnan province adjacent to Myanmar reported indigenous malaria cases in the four consecutive years from 2011 to 2014.

CONCLUSIONS:The scale and extent of malaria occurrence in the international land border counties of China decreased dramatically during the elimination period. However, several high-risk counties, especially along the China-Myanmar border, still face a persistent risk of malaria introduction and transmission. The study emphasizes the importance and urgency of cross-border cooperation between neighbouring countries to jointly face malaria threats to elimination goals.
1475-2875
1-9
Zhang, Qian
5768ab4e-5e98-4a28-bf41-56a8abb54c64
Sun, Junling
4f56058d-f603-4758-9b92-873ac36de30f
Zhang, Zike
85c05276-59dd-4033-82c9-4d33e872906b
Geng, Qibin
8c0f930c-f49f-40df-b954-fddd27eb9a76
Lai, Shengjie
b57a5fe8-cfb6-4fa7-b414-a98bb891b001
Hu, Wenbiao
ac87e378-67ae-4fa0-abf1-4cefcb0870f9
Clements, Archie C.A.
e1cd8912-66b0-4b99-8167-b68ca3d42ec4
Li, Zhongjie
f89a98f7-f6d3-4312-995a-bc658ae9a93f
Zhang, Qian
5768ab4e-5e98-4a28-bf41-56a8abb54c64
Sun, Junling
4f56058d-f603-4758-9b92-873ac36de30f
Zhang, Zike
85c05276-59dd-4033-82c9-4d33e872906b
Geng, Qibin
8c0f930c-f49f-40df-b954-fddd27eb9a76
Lai, Shengjie
b57a5fe8-cfb6-4fa7-b414-a98bb891b001
Hu, Wenbiao
ac87e378-67ae-4fa0-abf1-4cefcb0870f9
Clements, Archie C.A.
e1cd8912-66b0-4b99-8167-b68ca3d42ec4
Li, Zhongjie
f89a98f7-f6d3-4312-995a-bc658ae9a93f

Zhang, Qian, Sun, Junling, Zhang, Zike, Geng, Qibin, Lai, Shengjie, Hu, Wenbiao, Clements, Archie C.A. and Li, Zhongjie (2016) Risk assessment of malaria in land border regions of China in the context of malaria elimination. Malaria Journal, 15 (546), 1-9. (doi:10.1186/s12936-016-1590-1). (PMID:27825379)

Record type: Article

Abstract

BACKGROUND:Cross-border malaria transmission poses a challenge for countries to achieve and maintain malaria elimination. Because of a dramatic increase of cross-border population movement between China and 14 neighbouring countries, the malaria epidemic risk in China's land border regions needs to be understood.

METHODS: In this study, individual case-based epidemiological data on malaria in the 136 counties of China with international land borders, from 2011 to 2014, were extracted from the National Infectious Disease Information System. The Plasmodium species, seasonality, spatiotemporal distribution and changing features of imported and indigenous cases were analysed using descriptive spatial and temporal methods.

RESULTS:A total of 1948 malaria cases were reported, with 1406 (72.2%) imported cases and 542 (27.8%) indigenous cases. Plasmodium vivax is the predominant species, with 1536 malaria cases occurrence (78.9%), following by Plasmodium falciparum (361 cases, 18.5%), and the others (51 cases, 2.6%). The magnitude and geographic distribution of malaria in land border counties shrunk sharply during the elimination period. Imported malaria cases were with a peak of 546 cases in 2011, decreasing yearly in the following years. The number of counties with imported cases decreased from 28 counties in 2011 to 26 counties in 2014. Indigenous malaria cases presented a markedly decreasing trend, with 319 indigenous cases in 2011 reducing to only 33 indigenous cases in 2014. The number of counties with indigenous cases reduced from 26 counties in 2011 to 10 counties in 2014. However, several bordering counties of Yunnan province adjacent to Myanmar reported indigenous malaria cases in the four consecutive years from 2011 to 2014.

CONCLUSIONS:The scale and extent of malaria occurrence in the international land border counties of China decreased dramatically during the elimination period. However, several high-risk counties, especially along the China-Myanmar border, still face a persistent risk of malaria introduction and transmission. The study emphasizes the importance and urgency of cross-border cooperation between neighbouring countries to jointly face malaria threats to elimination goals.

Text
2016- Malaria J- Risk assessment of malaria in land border regions of China in the context of malaria elimination.pdf - Version of Record
Available under License Creative Commons Attribution.
Download (1MB)

More information

Accepted/In Press date: 28 October 2016
e-pub ahead of print date: 8 November 2016
Organisations: WorldPop, Population, Health & Wellbeing (PHeW)

Identifiers

Local EPrints ID: 405109
URI: https://eprints.soton.ac.uk/id/eprint/405109
ISSN: 1475-2875
PURE UUID: 86d7e449-f3fd-4a30-98c2-42c94bc5a858
ORCID for Shengjie Lai: ORCID iD orcid.org/0000-0001-9781-8148

Catalogue record

Date deposited: 27 Jan 2017 09:55
Last modified: 15 Aug 2019 00:22

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×