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Management of child MDR-TB contacts across countries in the WHO European Region: a survey of current practice

Management of child MDR-TB contacts across countries in the WHO European Region: a survey of current practice
Management of child MDR-TB contacts across countries in the WHO European Region: a survey of current practice
The World Health Organization European Region has one of the highest rates of multidrug-resistant (MDR) tuberculosis (TB) in the world, resulting in many vulnerable children getting exposed each year. Evidence for preventive therapy following MDR-TB exposure is limited and current guidance is conflicting. An online survey was performed to determine clinical practice in this region. Seventy-two clinicians from 25 countries participated. Practices related to screening and decision-making were highly variable. Just over half were providing preventive therapy for MDR-TB-exposed children; the only characteristic associated with provision was practice within the European Union (adjusted odds ratio: 4.07; 95% confidence interval: 1.33-12.5).
1027-3719
774-777
Turkova, Anna
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Tebruegge, Marc
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Brinkmann, Folke
3e23e423-4061-4b9f-824c-94c6457b553d
Tsolia, Maria
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Mouchet, Francoise
fec65074-5212-4693-858c-8453f6babe9e
Kampmann, Beate
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Seddon, James
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Turkova, Anna
b57cb914-e364-4205-80b9-deb3f486f560
Tebruegge, Marc
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Brinkmann, Folke
3e23e423-4061-4b9f-824c-94c6457b553d
Tsolia, Maria
537d379f-d08e-4d9a-9ef1-0d4310b6eb28
Mouchet, Francoise
fec65074-5212-4693-858c-8453f6babe9e
Kampmann, Beate
d77ddb9c-c3c5-4245-ae0d-698b1ab2c4b8
Seddon, James
44f4df8b-0442-49b7-9dd9-e3ae6410c9b3

Turkova, Anna, Tebruegge, Marc, Brinkmann, Folke, Tsolia, Maria, Mouchet, Francoise, Kampmann, Beate and Seddon, James (2017) Management of child MDR-TB contacts across countries in the WHO European Region: a survey of current practice. International Journal of Tuberculosis and Lung Disease, 21 (7), 774-777. (doi:10.5588/ijtld.16.0949).

Record type: Article

Abstract

The World Health Organization European Region has one of the highest rates of multidrug-resistant (MDR) tuberculosis (TB) in the world, resulting in many vulnerable children getting exposed each year. Evidence for preventive therapy following MDR-TB exposure is limited and current guidance is conflicting. An online survey was performed to determine clinical practice in this region. Seventy-two clinicians from 25 countries participated. Practices related to screening and decision-making were highly variable. Just over half were providing preventive therapy for MDR-TB-exposed children; the only characteristic associated with provision was practice within the European Union (adjusted odds ratio: 4.07; 95% confidence interval: 1.33-12.5).

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R1_Contacts Survey_IJTLD_final - accepted version - combined - Accepted Manuscript
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More information

Accepted/In Press date: 7 March 2017
e-pub ahead of print date: 1 July 2017
Published date: 1 July 2017
Organisations: Allergy & Inflammation Research

Identifiers

Local EPrints ID: 406142
URI: http://eprints.soton.ac.uk/id/eprint/406142
ISSN: 1027-3719
PURE UUID: 02b27910-f395-48ac-bec2-ace5f45455cb

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Date deposited: 10 Mar 2017 10:40
Last modified: 16 Mar 2024 05:07

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Contributors

Author: Anna Turkova
Author: Marc Tebruegge
Author: Folke Brinkmann
Author: Maria Tsolia
Author: Francoise Mouchet
Author: Beate Kampmann
Author: James Seddon

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