Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: acute-phase outcomes
Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: acute-phase outcomes
Background: Cognitive—behavioural therapy (CBT) improves persistent psychotic symptoms.
Aims: To test the effectiveness of added CBT in accelerating remission from acute psychotic symptoms in early schizophrenia.
Method: A 5-week CBT programme plus routine care was compared with supportive counselling plus routine care and routine care alone in a multi-centre trial randomising 315 people with DSM—IV schizophrenia and related disorders in their first (83%) or second acute admission. Outcome assessments were blinded.
Results: Linear regression over 70 days showed predicted trends towards faster improvement in the CBT group.
Uncorrected univariate comparisons showed significant benefits at 4 but not 6 weeks for CBTv. routine care alone on Positive and Negative Syndrome Scale total and positive sub-scale scores and delusion score and benefits v. supportive counselling for auditory hallucinations score.
Conclusions: CBT shows transient advantages over routine care alone or supportive counselling in speeding remission from acute symptoms in early schizophrenia.
s91-s97
Lewis, Shôn
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Tarrier, Nicholas
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Haddock, Gillian
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Bentall, Richard
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Kinderman, Peter
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Kingdon, David
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Siddle, Ronald
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Drake, Richard
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Everitt, Julie
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Leadley, Karen
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Benn, Andy
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Grazebrook, Katy
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Haley, Cliff
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Akhtar, Shahid
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Davies, Linda
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Palmer, Steve
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Faragher, Brian
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Dunn, Graham
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September 2002
Lewis, Shôn
cf54165f-32db-4bcb-b619-9d452294690f
Tarrier, Nicholas
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Haddock, Gillian
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Bentall, Richard
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Kinderman, Peter
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Kingdon, David
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Siddle, Ronald
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Drake, Richard
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Everitt, Julie
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Leadley, Karen
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Benn, Andy
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Grazebrook, Katy
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Haley, Cliff
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Akhtar, Shahid
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Davies, Linda
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Palmer, Steve
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Faragher, Brian
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Dunn, Graham
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Lewis, Shôn, Tarrier, Nicholas, Haddock, Gillian, Bentall, Richard, Kinderman, Peter, Kingdon, David, Siddle, Ronald, Drake, Richard, Everitt, Julie, Leadley, Karen, Benn, Andy, Grazebrook, Katy, Haley, Cliff, Akhtar, Shahid, Davies, Linda, Palmer, Steve, Faragher, Brian and Dunn, Graham
(2002)
Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia: acute-phase outcomes.
British Journal of Psychiatry, 181 (Supplement 43), .
Abstract
Background: Cognitive—behavioural therapy (CBT) improves persistent psychotic symptoms.
Aims: To test the effectiveness of added CBT in accelerating remission from acute psychotic symptoms in early schizophrenia.
Method: A 5-week CBT programme plus routine care was compared with supportive counselling plus routine care and routine care alone in a multi-centre trial randomising 315 people with DSM—IV schizophrenia and related disorders in their first (83%) or second acute admission. Outcome assessments were blinded.
Results: Linear regression over 70 days showed predicted trends towards faster improvement in the CBT group.
Uncorrected univariate comparisons showed significant benefits at 4 but not 6 weeks for CBTv. routine care alone on Positive and Negative Syndrome Scale total and positive sub-scale scores and delusion score and benefits v. supportive counselling for auditory hallucinations score.
Conclusions: CBT shows transient advantages over routine care alone or supportive counselling in speeding remission from acute symptoms in early schizophrenia.
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Published date: September 2002
Additional Information:
Presented in part at the European First Episode Schizophrenia Network Meeting, Whistler BC, Canada, 28 April 2001
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Local EPrints ID: 40637
URI: http://eprints.soton.ac.uk/id/eprint/40637
ISSN: 0007-1250
PURE UUID: a88b06cc-9040-4e36-a3ff-5f1735f7a1b4
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Date deposited: 07 Jul 2006
Last modified: 15 Mar 2024 08:21
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Contributors
Author:
Shôn Lewis
Author:
Nicholas Tarrier
Author:
Gillian Haddock
Author:
Richard Bentall
Author:
Peter Kinderman
Author:
David Kingdon
Author:
Ronald Siddle
Author:
Richard Drake
Author:
Julie Everitt
Author:
Karen Leadley
Author:
Andy Benn
Author:
Katy Grazebrook
Author:
Cliff Haley
Author:
Shahid Akhtar
Author:
Linda Davies
Author:
Steve Palmer
Author:
Brian Faragher
Author:
Graham Dunn
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