Caenorhabditis elegans feeding behaviours
Caenorhabditis elegans feeding behaviours
The microscopic free-living nematode worm Caenorhabditis elegans was the first metazoan to have its genome sequenced and for many decades has served as a genetically tractable model for the investigation of neural mechanisms of behavioural plasticity. Many of its behaviours involve the detection of its food, bacteria, which are ingested and transported to the intestine by a muscular pharynx. The structure of the pharynx and the circuitry of the pharyngeal nervous system which regulates pharyngeal activity have been described in some detail. This has provided a platform for understanding how this simple organism finely tunes its feeding behaviour in response to the changing availability and quality of its food, and in the context of its own nutritional status. This resonates with fundamental principles of energy homeostasis that occur throughout the animal kingdom.
Holden-Dye, Linda
8032bf60-5db6-40cb-b71c-ddda9d212c8e
Walker, Robert
9368ac2d-f1e9-4bd9-a4b4-4a161c4aa140
2017
Holden-Dye, Linda
8032bf60-5db6-40cb-b71c-ddda9d212c8e
Walker, Robert
9368ac2d-f1e9-4bd9-a4b4-4a161c4aa140
Holden-Dye, Linda and Walker, Robert
(2017)
Caenorhabditis elegans feeding behaviours.
Oxford Research Encyclopedia of Neuroscience.
Abstract
The microscopic free-living nematode worm Caenorhabditis elegans was the first metazoan to have its genome sequenced and for many decades has served as a genetically tractable model for the investigation of neural mechanisms of behavioural plasticity. Many of its behaviours involve the detection of its food, bacteria, which are ingested and transported to the intestine by a muscular pharynx. The structure of the pharynx and the circuitry of the pharyngeal nervous system which regulates pharyngeal activity have been described in some detail. This has provided a platform for understanding how this simple organism finely tunes its feeding behaviour in response to the changing availability and quality of its food, and in the context of its own nutritional status. This resonates with fundamental principles of energy homeostasis that occur throughout the animal kingdom.
Text
DALLIERE Caenorhabditis elegans feeding AAM
- Accepted Manuscript
More information
Accepted/In Press date: 23 February 2017
Published date: 2017
Organisations:
Biomedicine, Centre for Biological Sciences
Identifiers
Local EPrints ID: 406590
URI: http://eprints.soton.ac.uk/id/eprint/406590
PURE UUID: 97a2df31-5d4b-4535-a56a-c766133c0ba3
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Date deposited: 18 Mar 2017 02:23
Last modified: 16 Mar 2024 05:07
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