The University of Southampton
University of Southampton Institutional Repository

Common hereditary cancers and implications for primary care

Common hereditary cancers and implications for primary care
Common hereditary cancers and implications for primary care
The identification of genes that place individuals at high risk of breast, ovarian, and colorectal cancer has greatly advanced our understanding of cancer predisposition over the past decade. This knowledge has received much attention from the media, and referrals to geneticists and surgeons, and requests for genetic testing, have risen.
We review the published evidence for the management of people at increased risk of hereditary cancers, to draw attention to areas of uncertainty and to discuss implications for primary care. We focus on common inherited cancers, since they will have the greatest effect on clinical practice over the next decade. Cancer genetics offers a model of how information on the genetics of other common diseases could affect primary care in the future.
Strategies to support the integration of genetic medicine in primary care are needed to enable primary-care practitioners to identify individuals at raised genetic risk and to reassure patients for whom genetic testing and increased surveillance offer little benefit.
0140-6736
56-63
Emery, Jon
383d1dac-36a8-4ead-99f6-cad5a01730d4
Lucassen, Anneke
2eb85efc-c6e8-4c3f-b963-0290f6c038a5
Murphy, Michael
ceb616d9-ead2-4c6e-8b55-80e91c96f601
Emery, Jon
383d1dac-36a8-4ead-99f6-cad5a01730d4
Lucassen, Anneke
2eb85efc-c6e8-4c3f-b963-0290f6c038a5
Murphy, Michael
ceb616d9-ead2-4c6e-8b55-80e91c96f601

Emery, Jon, Lucassen, Anneke and Murphy, Michael (2001) Common hereditary cancers and implications for primary care. The Lancet, 358 (9275), 56-63. (doi:10.1016/S0140-6736(00)05257-0).

Record type: Article

Abstract

The identification of genes that place individuals at high risk of breast, ovarian, and colorectal cancer has greatly advanced our understanding of cancer predisposition over the past decade. This knowledge has received much attention from the media, and referrals to geneticists and surgeons, and requests for genetic testing, have risen.
We review the published evidence for the management of people at increased risk of hereditary cancers, to draw attention to areas of uncertainty and to discuss implications for primary care. We focus on common inherited cancers, since they will have the greatest effect on clinical practice over the next decade. Cancer genetics offers a model of how information on the genetics of other common diseases could affect primary care in the future.
Strategies to support the integration of genetic medicine in primary care are needed to enable primary-care practitioners to identify individuals at raised genetic risk and to reassure patients for whom genetic testing and increased surveillance offer little benefit.

This record has no associated files available for download.

More information

Published date: 2001
Additional Information: Review
Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 40680
URI: http://eprints.soton.ac.uk/id/eprint/40680
ISSN: 0140-6736
PURE UUID: 4be5b8e9-b1bb-4352-86ee-0bc1a7a0d2f6
ORCID for Anneke Lucassen: ORCID iD orcid.org/0000-0003-3324-4338

Catalogue record

Date deposited: 07 Jul 2006
Last modified: 16 Aug 2024 01:38

Export record

Altmetrics

Contributors

Author: Jon Emery
Author: Anneke Lucassen ORCID iD
Author: Michael Murphy

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×