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Common hereditary cancers and implications for primary care

Record type: Article

The identification of genes that place individuals at high risk of breast, ovarian, and colorectal cancer has greatly advanced our understanding of cancer predisposition over the past decade. This knowledge has received much attention from the media, and referrals to geneticists and surgeons, and requests for genetic testing, have risen.
We review the published evidence for the management of people at increased risk of hereditary cancers, to draw attention to areas of uncertainty and to discuss implications for primary care. We focus on common inherited cancers, since they will have the greatest effect on clinical practice over the next decade. Cancer genetics offers a model of how information on the genetics of other common diseases could affect primary care in the future.
Strategies to support the integration of genetic medicine in primary care are needed to enable primary-care practitioners to identify individuals at raised genetic risk and to reassure patients for whom genetic testing and increased surveillance offer little benefit.

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Citation

Emery, Jon, Lucassen, Anneke and Murphy, Michael (2001) Common hereditary cancers and implications for primary care The Lancet, 358, (9275), pp. 56-63. (doi:10.1016/S0140-6736(00)05257-0).

More information

Published date: 2001
Additional Information: Review
Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 40680
URI: http://eprints.soton.ac.uk/id/eprint/40680
ISSN: 0140-6736
PURE UUID: 4be5b8e9-b1bb-4352-86ee-0bc1a7a0d2f6

Catalogue record

Date deposited: 07 Jul 2006
Last modified: 17 Jul 2017 15:33

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Contributors

Author: Jon Emery
Author: Anneke Lucassen
Author: Michael Murphy

University divisions


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