The University of Southampton
University of Southampton Institutional Repository

Tics and Tourette Syndrome

Tics and Tourette Syndrome
Tics and Tourette Syndrome
Gilles de la Tourette syndrome is a neurodevelopmental disorder, characterized by a wide variety of symptoms, ranging from simple motor and phonic tics to complex movement cascades, and echophenomena and coprophenomena. Moreover, Tourette syndrome is frequently accompanied by obsessive-compulsive disorder and attention-deficit hyperactivity disorder, often leading to a higher psychosocial impairment than tics. Tics are typically associated with an uncontrollable, uncomfortable, premonitory urge to execute the tic. Although Tourette syndrome is highly heritable, no single gene could be identified as a main risk factor for developing tics, yet. Moreover, the severity of Tourette syndrome can be influenced by environmental factors such as stress or attention. Pathophysiologically, Tourette syndrome has been repeatedly associated with abnormalities in cortico-striatal-thalamo-cortical loops and the dopaminergic neurotransmitter system. In accordance with these observations, successful treatment measures include neuroleptics, behavioural therapy and in severe cases tetra-hydro-cannabinol and deep brain stimulation of some of the structures in cortico-striatal-thalamo-cortical loops.
291-302
Springer Wien
Brandt, Valerie
e41f5832-70e4-407d-8a15-85b861761656
Münchau, Alexander
3254c1b7-9fd4-417d-96e2-b7bc1fe3c736
Falup-Pecurariu, C.
Ferreira, J.
Martinez-Martin, P.
Chaudhuri, K.R.
Brandt, Valerie
e41f5832-70e4-407d-8a15-85b861761656
Münchau, Alexander
3254c1b7-9fd4-417d-96e2-b7bc1fe3c736
Falup-Pecurariu, C.
Ferreira, J.
Martinez-Martin, P.
Chaudhuri, K.R.

Brandt, Valerie and Münchau, Alexander (2017) Tics and Tourette Syndrome. In, Falup-Pecurariu, C., Ferreira, J., Martinez-Martin, P. and Chaudhuri, K.R. (eds.) Movement Disorders Curricula. 1 ed. Springer Wien, pp. 291-302. (doi:10.1007/978-3-7091-1628-9).

Record type: Book Section

Abstract

Gilles de la Tourette syndrome is a neurodevelopmental disorder, characterized by a wide variety of symptoms, ranging from simple motor and phonic tics to complex movement cascades, and echophenomena and coprophenomena. Moreover, Tourette syndrome is frequently accompanied by obsessive-compulsive disorder and attention-deficit hyperactivity disorder, often leading to a higher psychosocial impairment than tics. Tics are typically associated with an uncontrollable, uncomfortable, premonitory urge to execute the tic. Although Tourette syndrome is highly heritable, no single gene could be identified as a main risk factor for developing tics, yet. Moreover, the severity of Tourette syndrome can be influenced by environmental factors such as stress or attention. Pathophysiologically, Tourette syndrome has been repeatedly associated with abnormalities in cortico-striatal-thalamo-cortical loops and the dopaminergic neurotransmitter system. In accordance with these observations, successful treatment measures include neuroleptics, behavioural therapy and in severe cases tetra-hydro-cannabinol and deep brain stimulation of some of the structures in cortico-striatal-thalamo-cortical loops.

This record has no associated files available for download.

More information

Published date: 2017
Organisations: Psychology

Identifiers

Local EPrints ID: 407013
URI: http://eprints.soton.ac.uk/id/eprint/407013
PURE UUID: 91e3e932-4359-424b-9710-4cf31998cfe9

Catalogue record

Date deposited: 29 Mar 2017 01:10
Last modified: 15 Mar 2024 12:38

Export record

Altmetrics

Contributors

Author: Valerie Brandt
Author: Alexander Münchau
Editor: C. Falup-Pecurariu
Editor: J. Ferreira
Editor: P. Martinez-Martin
Editor: K.R. Chaudhuri

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×