Leaper, D., Paggi, B., Compton, G.A., Orsted, H., Teot, L. and Ockenfels, H.M.
Growth factors and interactive dressings in wound repair
The EWMA Journal, 2, (2), .
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The work of Winter in the 1960s established the concept of ‘moist wound healing. This principle has contributed to the development of the plethora of products that are currently available, among which are hydrogels, hydrocolloids, alginates, and foams or films. Some of these products also incorporate antiseptics in their delivery systems.
However, it has become evident that ‘moist wound healing’ along may not be sufficient to improve wound healing outcomes. This is because each wound type can have different barriers to healing. Closure of surgical wounds is inhibited by poor perfusion and infection. Delay in healing of a chronic wound, can result from pressure, venous hypertension, poorly controlled diabetes, inadequacy of arterial inflow, vasculitis, repeated trauma or failure to debride necrotic tissue.
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