Maternal nutritional status during pregnancy and infant immune response to routine childhood vaccinations
Maternal nutritional status during pregnancy and infant immune response to routine childhood vaccinations
To systematically review the association between maternal nutritional status in pregnancy and infant immune response to childhood vaccines. We reviewed literature on maternal nutrition during pregnancy, fetal immune system and vaccines and possible relationships. Thereafter, we undertook a systematic review of the literature of maternal nutritional status and infant vaccine response, extracted relevant information, assessed quality of the nine papers identified and present findings in a narrative format. From limited evidence of average quality, intrauterine nutrition deficiency could lead to functional deficit in the infant's immune function; child vaccine response may thus be negatively affected by maternal malnutrition. Response to childhood vaccination may be associated with fetal and early life environment; evaluation of programs should take this into account.
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Obanewa, Olayinka
25ae883c-6381-44c3-b550-c09b59df4f61
Newell, Marie-Louise
c6ff99dd-c23b-4fef-a846-a221fe2522b3
Obanewa, Olayinka
25ae883c-6381-44c3-b550-c09b59df4f61
Newell, Marie-Louise
c6ff99dd-c23b-4fef-a846-a221fe2522b3
Obanewa, Olayinka and Newell, Marie-Louise
(2017)
Maternal nutritional status during pregnancy and infant immune response to routine childhood vaccinations.
Future Virology, .
(doi:10.2217/fvl-2017-0021).
Abstract
To systematically review the association between maternal nutritional status in pregnancy and infant immune response to childhood vaccines. We reviewed literature on maternal nutrition during pregnancy, fetal immune system and vaccines and possible relationships. Thereafter, we undertook a systematic review of the literature of maternal nutritional status and infant vaccine response, extracted relevant information, assessed quality of the nine papers identified and present findings in a narrative format. From limited evidence of average quality, intrauterine nutrition deficiency could lead to functional deficit in the infant's immune function; child vaccine response may thus be negatively affected by maternal malnutrition. Response to childhood vaccination may be associated with fetal and early life environment; evaluation of programs should take this into account.
Text
070617a- BlindedMaternal-nutrition-and-infant--immune-response-to-routine-childhood--vaccinations-300517 (1) MLN
- Accepted Manuscript
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Accepted/In Press date: 8 June 2017
e-pub ahead of print date: 29 September 2017
Organisations:
Human Development & Health
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Local EPrints ID: 410889
URI: http://eprints.soton.ac.uk/id/eprint/410889
PURE UUID: 745f6fb8-e3bc-414e-bb4d-f390b439e460
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Date deposited: 09 Jun 2017 16:31
Last modified: 16 Mar 2024 05:26
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Author:
Olayinka Obanewa
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