Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1
Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1
The erythroid transcription factor erythroid factor-1 (EF1) plays a critical role in the transcription of erythroid-specific genes. Here we report the presence of a factor with the mobility and sequence-specific DNA-binding characteristics of EF1 at low abundance in a wide variety of non-erythroid cell types. This is the first report of an EF1-like activity in non-erythroid cells and indicates that this factor may play a role in the regulation of genes expressed in such cells.
Animals, Binding, Competitive, Cell Line, Cell Nucleus, DNA, DNA-Binding Proteins, Electrophoresis, Polyacrylamide Gel, Erythroid-Specific DNA-Binding Factors, HeLa Cells, Humans, Leukemia, Erythroblastic, Acute, Mice, T-Lymphocytes, Teratoma, Transcription Factors, Tumor Cells, Cultured, Journal Article, Research Support, Non-U.S. Gov't
543-5
Perkins, N D
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Orchard, K H
794654ab-d6cc-488a-ac11-c9217433c7a2
Collins, M L
39c341a9-3dab-40e3-9d5a-b77cdb360ffd
Latchman, D S
917ce95a-ac18-47da-881d-4fece00ae530
Goodwin, G H
92787fdd-1a5f-4e45-bbbe-c31b720b8d89
15 July 1990
Perkins, N D
cd0fd1b8-1a84-45d3-aef1-6cee63249309
Orchard, K H
794654ab-d6cc-488a-ac11-c9217433c7a2
Collins, M L
39c341a9-3dab-40e3-9d5a-b77cdb360ffd
Latchman, D S
917ce95a-ac18-47da-881d-4fece00ae530
Goodwin, G H
92787fdd-1a5f-4e45-bbbe-c31b720b8d89
Perkins, N D, Orchard, K H, Collins, M L, Latchman, D S and Goodwin, G H
(1990)
Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1.
Biochemical Journal, 269 (2), .
Abstract
The erythroid transcription factor erythroid factor-1 (EF1) plays a critical role in the transcription of erythroid-specific genes. Here we report the presence of a factor with the mobility and sequence-specific DNA-binding characteristics of EF1 at low abundance in a wide variety of non-erythroid cell types. This is the first report of an EF1-like activity in non-erythroid cells and indicates that this factor may play a role in the regulation of genes expressed in such cells.
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Published date: 15 July 1990
Keywords:
Animals, Binding, Competitive, Cell Line, Cell Nucleus, DNA, DNA-Binding Proteins, Electrophoresis, Polyacrylamide Gel, Erythroid-Specific DNA-Binding Factors, HeLa Cells, Humans, Leukemia, Erythroblastic, Acute, Mice, T-Lymphocytes, Teratoma, Transcription Factors, Tumor Cells, Cultured, Journal Article, Research Support, Non-U.S. Gov't
Organisations:
Cancer Sciences, Electronics & Computer Science
Identifiers
Local EPrints ID: 411595
URI: http://eprints.soton.ac.uk/id/eprint/411595
ISSN: 0264-6021
PURE UUID: eb3a3f70-e0cb-41fa-b5f7-9ebdbba9a955
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Date deposited: 21 Jun 2017 16:31
Last modified: 29 Jul 2022 01:39
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Contributors
Author:
N D Perkins
Author:
K H Orchard
Author:
M L Collins
Author:
D S Latchman
Author:
G H Goodwin
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