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A two-directional synthesis of (+)-β-isosparteine

Al-Saffar, Firas, Mohammed and Brown, Richard C.D. (2017) A two-directional synthesis of (+)-β-isosparteine Organic Letters, 19, (13), pp. 3502-3504. (doi:10.1021/acs.orglett.7b01475).

Record type: Article


A two-directional synthesis of (+)-β-isosparteine is described in five steps from glutaric acid, where the entire carbon and nitrogen backbone of the alkaloid, possessing the requisite relative and absolute stereochemistry at its four stereogenic centers, is assembled using a double imino-aldol reaction.

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Accepted/In Press date: 9 June 2017
e-pub ahead of print date: 13 June 2017


Local EPrints ID: 412136
ISSN: 1523-7060
PURE UUID: c9a58328-c921-422f-b8fa-851f61cfbc24
ORCID for Richard C.D. Brown: ORCID iD

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Date deposited: 11 Jul 2017 16:31
Last modified: 09 Oct 2017 16:30

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Author: Firas, Mohammed Al-Saffar

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