Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications
Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications
Novel Poly(3-hydroxybutyrate)/Poly(3-hydroxyoctanoate) blends were developed with varying amounts of Poly(3-hydroxyoctanoate), P(3HO) and Poly(3-hydroxybutyrate), P(3HB) for their potential use in various medical applications. These blend films exhibited higher tensile strength and Young’s modulus values
compared to neat P(3HO). The overall protein adsorption and % cell viability was also found to be significantly higher in the blend films than the neat P(3HO) film. Hydrolytic degradation was faster in the blend films and the degradation rate could potentially be tailored to achieve the optimum rate required for a particular medical application. Hence, these novel blends were found to be highly biocompatible with surface, mechanical and thermal properties suitable for a range of potential medical applications, a great step forward in the area of medical materials.
1340 - 1348
Stolz, Martin
7bfa1d59-511d-471b-96ce-679b343b5d1d
2 April 2013
Stolz, Martin
7bfa1d59-511d-471b-96ce-679b343b5d1d
Stolz, Martin
(2013)
Novel Poly(3-hydroxyoctanoate)/Poly(3-hydroxybutyrate) blends for medical applications.
Reactive and Functional Polymers, .
Abstract
Novel Poly(3-hydroxybutyrate)/Poly(3-hydroxyoctanoate) blends were developed with varying amounts of Poly(3-hydroxyoctanoate), P(3HO) and Poly(3-hydroxybutyrate), P(3HB) for their potential use in various medical applications. These blend films exhibited higher tensile strength and Young’s modulus values
compared to neat P(3HO). The overall protein adsorption and % cell viability was also found to be significantly higher in the blend films than the neat P(3HO) film. Hydrolytic degradation was faster in the blend films and the degradation rate could potentially be tailored to achieve the optimum rate required for a particular medical application. Hence, these novel blends were found to be highly biocompatible with surface, mechanical and thermal properties suitable for a range of potential medical applications, a great step forward in the area of medical materials.
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Published date: 2 April 2013
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Local EPrints ID: 412433
URI: http://eprints.soton.ac.uk/id/eprint/412433
ISSN: 1381-5148
PURE UUID: 1e1fca79-9828-43d2-b15a-0d458fb0f2da
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Date deposited: 17 Jul 2017 13:43
Last modified: 09 Jan 2022 03:32
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