This file contains the experimental data and the Matlab Routines used in Luis Blay-Esteban, Eda Dogan, Eduardo Rodríguez-López and Bharathram Ganapathisubramani (2017) Skin friction measurements in a turbulent boundary layer with zero-pressure-gradient under the influence of free-stream turbulence. Experiments in Fluids (2017) 58:115, DOI 10.1007/s00348-017-2397-8 The dataset contains 28 different cases for various combinations of freestream velocity and freestream turbulence intensity generated with an active grid. All the data are taken using hot-wire anemometry and oil-film interferometry. Then the skin friction obtained by the latter method is compared with the skin friction obtained from a fit to the mean velocity profile. The data is structured in 28 files corresponding to the various experimental cases. The header of the file is a summary of the experimental conditions (Friction coefficient, freestream turbulence, freestream velocity, wake parameter, boundary layer thickness, Reynolds number, etc.). The same notation of the paper is followed. Below that header the velocity profile for each case is expressed in wall units (normalized with the viscosity and the friction velocity obtained by the fitting process)