Customization of mechanical properties and porosity of bone tissue scaffold materials via Layer-by-Layer assembly of polymer-nanocomposite coatings
Customization of mechanical properties and porosity of bone tissue scaffold materials via Layer-by-Layer assembly of polymer-nanocomposite coatings
The aim of this preliminary study was to adapt Layer-by-Layer (LbL) assembly to fabricate nanocomposite coatings onto open-cell porous structures, enabling customization of mechanical properties and porosity to obtain materials suitable for bone tissue scaffold applications. LbL assembly is a well-established method for fabricating multilayer films with nanometre scale precision over thickness that is based on electrostatic attractions and involves the adsorption of oppositely charged electrolytes onto a substrate. Using LbL assembly, polymer-nanoclay composite coatings were deposited onto open-cell foam substrates. The elastic modulus of coated specimens in compression was improved from 0.078 MPa to 1.736 MPa. The results suggest that polymer-nanoclay coatings deposited via LbL assembly have the potential to improve mechanical properties of porous substrates and fabricate materials with mechanical properties comparable to that of a cancellous bone tissue upon deposition of a sufficient number of multilayers.
67-72
Materials Research Society
Ziminska, M.
a53248bb-9825-4aa4-a9ea-2701a7f618f1
Dunne, N.
a75d99c0-e037-457d-87a9-2a4aec576a25
Hamilton, A.
9088cf01-8d7f-45f0-af56-b4784227447c
1 October 2015
Ziminska, M.
a53248bb-9825-4aa4-a9ea-2701a7f618f1
Dunne, N.
a75d99c0-e037-457d-87a9-2a4aec576a25
Hamilton, A.
9088cf01-8d7f-45f0-af56-b4784227447c
Ziminska, M., Dunne, N. and Hamilton, A.
(2015)
Customization of mechanical properties and porosity of bone tissue scaffold materials via Layer-by-Layer assembly of polymer-nanocomposite coatings.
In Foundations of Bio/Nano Interfaces - Synthesis, Modeling, Design Principles and Applications.
vol. 1793,
Materials Research Society.
.
(doi:10.1557/opl.2015.827).
Record type:
Conference or Workshop Item
(Paper)
Abstract
The aim of this preliminary study was to adapt Layer-by-Layer (LbL) assembly to fabricate nanocomposite coatings onto open-cell porous structures, enabling customization of mechanical properties and porosity to obtain materials suitable for bone tissue scaffold applications. LbL assembly is a well-established method for fabricating multilayer films with nanometre scale precision over thickness that is based on electrostatic attractions and involves the adsorption of oppositely charged electrolytes onto a substrate. Using LbL assembly, polymer-nanoclay composite coatings were deposited onto open-cell foam substrates. The elastic modulus of coated specimens in compression was improved from 0.078 MPa to 1.736 MPa. The results suggest that polymer-nanoclay coatings deposited via LbL assembly have the potential to improve mechanical properties of porous substrates and fabricate materials with mechanical properties comparable to that of a cancellous bone tissue upon deposition of a sufficient number of multilayers.
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Published date: 1 October 2015
Venue - Dates:
2015 MRS Spring Meeting, , San Francisco, United States, 2015-04-06 - 2015-04-10
Identifiers
Local EPrints ID: 413156
URI: http://eprints.soton.ac.uk/id/eprint/413156
PURE UUID: 3b026872-d23c-4c35-9bc2-bf112ae53182
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Date deposited: 16 Aug 2017 16:30
Last modified: 06 Jun 2024 01:59
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Author:
M. Ziminska
Author:
N. Dunne
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