The University of Southampton
University of Southampton Institutional Repository

Mechanical and tribological properties of poly(hydroxyethyl methacrylate) hydrogels as articular cartilage substitutes

Mechanical and tribological properties of poly(hydroxyethyl methacrylate) hydrogels as articular cartilage substitutes
Mechanical and tribological properties of poly(hydroxyethyl methacrylate) hydrogels as articular cartilage substitutes
Poly(hydroxyethyl methacrylate) (p(HEMA)) hydrogels have been proposed as promising biomaterials to replace damaged articular cartilage. A major obstacle to their use as replacement bearing tissue is their poor mechanical properties in comparison with healthy articular cartilage. The purpose of this study was to obtain p(HEMA) hydrogels with physicochemical and mechanical properties close to healthy articular cartilage, by introducing a hydrophilic monomer, namely acrylic acid (AA). Formulations of hydrogels with different amounts of hydrophilic monomer (acrylic acid, AA) were synthesized and tested: p(HEMA), p(HEMA-co-5%AA), p(HEMA-co-25%AA). The macro-mechanical tests were reproduced at nanoscale in order to verify if the superficial properties of the hydrogels are similar to the bulk ones.
0301-679X
215-224
Bostan, L.
9b269056-e210-4ab7-815a-f373528dcd66
Trunfio-Sfarghiu, A.-M.
355c5126-1ac4-42b0-bef1-3f4ffccd7d23
Verestiuc, L.
16dd969a-2410-45b9-bf0f-e31324b8dcb6
Popa, M.I.
d3a190fb-46c1-4649-ba4e-2f1caa2bfbd3
Munteanu, F.
921b7645-333b-41b8-92d2-936ce3e2c08b
Rieu, J.-P.
8046e01c-30bc-482d-ae39-245c6ff204d8
Berthier, Y.
3b244fc9-1770-4415-b5bb-e8e087c5588a
Bostan, L.
9b269056-e210-4ab7-815a-f373528dcd66
Trunfio-Sfarghiu, A.-M.
355c5126-1ac4-42b0-bef1-3f4ffccd7d23
Verestiuc, L.
16dd969a-2410-45b9-bf0f-e31324b8dcb6
Popa, M.I.
d3a190fb-46c1-4649-ba4e-2f1caa2bfbd3
Munteanu, F.
921b7645-333b-41b8-92d2-936ce3e2c08b
Rieu, J.-P.
8046e01c-30bc-482d-ae39-245c6ff204d8
Berthier, Y.
3b244fc9-1770-4415-b5bb-e8e087c5588a

Bostan, L., Trunfio-Sfarghiu, A.-M., Verestiuc, L., Popa, M.I., Munteanu, F., Rieu, J.-P. and Berthier, Y. (2012) Mechanical and tribological properties of poly(hydroxyethyl methacrylate) hydrogels as articular cartilage substitutes. Tribology International, 46 (1), 215-224. (doi:10.1016/j.triboint.2011.06.035).

Record type: Article

Abstract

Poly(hydroxyethyl methacrylate) (p(HEMA)) hydrogels have been proposed as promising biomaterials to replace damaged articular cartilage. A major obstacle to their use as replacement bearing tissue is their poor mechanical properties in comparison with healthy articular cartilage. The purpose of this study was to obtain p(HEMA) hydrogels with physicochemical and mechanical properties close to healthy articular cartilage, by introducing a hydrophilic monomer, namely acrylic acid (AA). Formulations of hydrogels with different amounts of hydrophilic monomer (acrylic acid, AA) were synthesized and tested: p(HEMA), p(HEMA-co-5%AA), p(HEMA-co-25%AA). The macro-mechanical tests were reproduced at nanoscale in order to verify if the superficial properties of the hydrogels are similar to the bulk ones.

Full text not available from this repository.

More information

Accepted/In Press date: 29 June 2011
e-pub ahead of print date: 20 July 2011
Published date: February 2012

Identifiers

Local EPrints ID: 413827
URI: https://eprints.soton.ac.uk/id/eprint/413827
ISSN: 0301-679X
PURE UUID: 0a23fa8f-7f40-4dad-8b8d-3fbbcad9d376
ORCID for L. Bostan: ORCID iD orcid.org/0000-0003-3882-2619

Catalogue record

Date deposited: 07 Sep 2017 16:31
Last modified: 20 Nov 2019 01:26

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×