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Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

Objective: To determine monoclonal antibody (mAb) features that predict fragment crystalizable (Fc)-mediated effector functions against HIV.

Antibody-dependent cellular cytotoxicity, Antibody-dependent cellular phagocytosis, Glycan structure, Monoclonal antibody
0269-9370
2523-2530
Chung, Amy W.
9a22d3da-12f2-42f1-bbfb-48550db5ceeb
Crispin, Matthew
cd980957-0943-4b89-b2b2-710f01f33bc9
Pritchard, Laura
bfa1d1b4-50b6-401f-b153-8c3322b2e726
Robinson, Hannah
5db3b2f0-c4a0-4cf3-a0e7-11a85972e000
Gorny, Miroslaw K.
b4ba4539-6497-4613-a0aa-5153580b9bed
Yu, Xiaojie
44d52374-eacc-4e23-b7da-c881e6d3a5dd
Bailey-Kellogg, Chris
b41c743e-a877-4e73-a59f-0de25ef9b31c
Ackerman, Margaret E.
b4a13358-a1ad-4b11-867b-e3102c2c9961
Scanlan, Chris
04dd1b57-b6fc-414c-8595-08310dbb3d32
Zolla-Pazner, Susan
72d31016-1554-4056-9b25-34bf93fc3807
Alter, Galit
2742863e-d5cf-4419-b922-9679afa2bc4b
Chung, Amy W.
9a22d3da-12f2-42f1-bbfb-48550db5ceeb
Crispin, Matthew
cd980957-0943-4b89-b2b2-710f01f33bc9
Pritchard, Laura
bfa1d1b4-50b6-401f-b153-8c3322b2e726
Robinson, Hannah
5db3b2f0-c4a0-4cf3-a0e7-11a85972e000
Gorny, Miroslaw K.
b4ba4539-6497-4613-a0aa-5153580b9bed
Yu, Xiaojie
44d52374-eacc-4e23-b7da-c881e6d3a5dd
Bailey-Kellogg, Chris
b41c743e-a877-4e73-a59f-0de25ef9b31c
Ackerman, Margaret E.
b4a13358-a1ad-4b11-867b-e3102c2c9961
Scanlan, Chris
04dd1b57-b6fc-414c-8595-08310dbb3d32
Zolla-Pazner, Susan
72d31016-1554-4056-9b25-34bf93fc3807
Alter, Galit
2742863e-d5cf-4419-b922-9679afa2bc4b

Chung, Amy W., Crispin, Matthew, Pritchard, Laura, Robinson, Hannah, Gorny, Miroslaw K., Yu, Xiaojie, Bailey-Kellogg, Chris, Ackerman, Margaret E., Scanlan, Chris, Zolla-Pazner, Susan and Alter, Galit (2014) Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function. AIDS, 28 (17), 2523-2530. (doi:10.1097/QAD.0000000000000444).

Record type: Article

Abstract

Objective: To determine monoclonal antibody (mAb) features that predict fragment crystalizable (Fc)-mediated effector functions against HIV.

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More information

Published date: 2014
Related URLs:
Keywords: Antibody-dependent cellular cytotoxicity, Antibody-dependent cellular phagocytosis, Glycan structure, Monoclonal antibody

Identifiers

Local EPrints ID: 414266
URI: http://eprints.soton.ac.uk/id/eprint/414266
DOI: doi:10.1097/QAD.0000000000000444
ISSN: 0269-9370
PURE UUID: 910154e8-b3e8-47ca-bae3-7e4075e884bc
ORCID for Matthew Crispin: ORCID iD orcid.org/0000-0002-1072-2694

Catalogue record

Date deposited: 21 Sep 2017 16:31
Last modified: 16 Mar 2024 04:30

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Contributors

Author: Amy W. Chung
Author: Matthew Crispin ORCID iD
Author: Laura Pritchard
Author: Hannah Robinson
Author: Miroslaw K. Gorny
Author: Xiaojie Yu
Author: Chris Bailey-Kellogg
Author: Margaret E. Ackerman
Author: Chris Scanlan
Author: Susan Zolla-Pazner
Author: Galit Alter

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