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FRAX Update

FRAX Update
FRAX Update
The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus). Since its release, models are now available for 63 countries, covering 79% of the world population. The website receives approximately 3 million visits annually. Following independent validation, FRAX has been incorporated into more than 80 guidelines worldwide. However, the application of FRAX in guidelines has been heterogeneous with the adoption of several different approaches to setting intervention thresholds. The relationship between FRAX and efficacy of intervention has been explored and is expected to influence treatment guidelines in the future. A more unified approach to setting intervention thresholds with FRAX is a research priority.
1094-6950
360-367
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215
Odén, Anders
cc56db15-a8d7-40f3-bd92-59d7a9abbf62
Leslie, William D.
5b2dd5d6-4569-40a3-a9b1-95152d11e4f1
McCloskey, Eugene V.
2f057a16-3d4e-4597-80c7-6ce47f969c78
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215
Odén, Anders
cc56db15-a8d7-40f3-bd92-59d7a9abbf62
Leslie, William D.
5b2dd5d6-4569-40a3-a9b1-95152d11e4f1
McCloskey, Eugene V.
2f057a16-3d4e-4597-80c7-6ce47f969c78

Kanis, John A., Harvey, Nicholas, Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V. (2017) FRAX Update. Journal of Clinical Densitometry, 20 (3), 360-367. (doi:10.1016/j.jocd.2017.06.022).

Record type: Article

Abstract

The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus). Since its release, models are now available for 63 countries, covering 79% of the world population. The website receives approximately 3 million visits annually. Following independent validation, FRAX has been incorporated into more than 80 guidelines worldwide. However, the application of FRAX in guidelines has been heterogeneous with the adoption of several different approaches to setting intervention thresholds. The relationship between FRAX and efficacy of intervention has been explored and is expected to influence treatment guidelines in the future. A more unified approach to setting intervention thresholds with FRAX is a research priority.

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e-pub ahead of print date: 18 July 2017

Identifiers

Local EPrints ID: 415023
URI: http://eprints.soton.ac.uk/id/eprint/415023
ISSN: 1094-6950
PURE UUID: 90b2b013-0e1c-4782-9649-dc1dabbc0cf9
ORCID for Nicholas Harvey: ORCID iD orcid.org/0000-0002-8194-2512

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Date deposited: 20 Oct 2017 16:32
Last modified: 16 Mar 2024 03:38

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Contributors

Author: John A. Kanis
Author: Nicholas Harvey ORCID iD
Author: Helena Johansson
Author: Anders Odén
Author: William D. Leslie
Author: Eugene V. McCloskey

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