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Systematic review: the impact of exercise on mesenteric blood flow in humans

Systematic review: the impact of exercise on mesenteric blood flow in humans
Systematic review: the impact of exercise on mesenteric blood flow in humans

Background

Exercise in the preoperative period, or prehabilitation, continues to evolve as an important tool in optimising patients awaiting major intra-abdominal surgery. It has been shown to reduce rates of post-operative morbidity and length of hospital stay. The mechanism by which this is achieved remains poorly understood. Adaptations in mesenteric flow in response to exercise may play a role in improving post-operative recovery by reducing rates of ileus and anastomotic leak.

Aims

To systematically review the existing literature to clarify the impact of exercise on mesenteric arterial blood flow using Doppler ultrasound.

Methods

PubMed, EMBASE and the Cochrane library were systematically searched to identify clinical trials using Doppler ultrasound to investigate the effect of exercise on flow through the superior mesenteric artery (SMA). Data were extracted including participant characteristics, frequency, intensity, timing and type of exercise and the effect on SMA flow. The quality of each study was assessed using the Downs and Black checklist.

Results

Sixteen studies, comprising 305 participants in total, were included. Methodological quality was generally poor. Healthy volunteers were used in twelve studies. SMA flow was found to be reduced in response to exercise in twelve studies, increased in one and unchanged in two studies. Clinical heterogeneity precluded a meta-analysis.

Conclusion

The weight of evidence suggests that superior mesenteric arterial flow is reduced immediately following exercise. Differences in frequency, intensity, timing and type of exercise make a consensus difficult. Further studies are warranted to provide a definitive understanding of the impact of exercise on mesenteric flow.
1123-6337
185-201
Knight, Katherina
e484071b-9189-47d5-8217-0a0c9e80a78d
Moug, Susan
f3a786d8-be95-4a10-8274-5a988e29af25
West, Malcolm
98b67e58-9875-4133-b236-8a10a0a12c04
Knight, Katherina
e484071b-9189-47d5-8217-0a0c9e80a78d
Moug, Susan
f3a786d8-be95-4a10-8274-5a988e29af25
West, Malcolm
98b67e58-9875-4133-b236-8a10a0a12c04

Knight, Katherina, Moug, Susan and West, Malcolm (2017) Systematic review: the impact of exercise on mesenteric blood flow in humans. Techniques in Coloproctology, 21 (3), 185-201. (doi:10.1007/s10151-017-1589-9).

Record type: Article

Abstract


Background

Exercise in the preoperative period, or prehabilitation, continues to evolve as an important tool in optimising patients awaiting major intra-abdominal surgery. It has been shown to reduce rates of post-operative morbidity and length of hospital stay. The mechanism by which this is achieved remains poorly understood. Adaptations in mesenteric flow in response to exercise may play a role in improving post-operative recovery by reducing rates of ileus and anastomotic leak.

Aims

To systematically review the existing literature to clarify the impact of exercise on mesenteric arterial blood flow using Doppler ultrasound.

Methods

PubMed, EMBASE and the Cochrane library were systematically searched to identify clinical trials using Doppler ultrasound to investigate the effect of exercise on flow through the superior mesenteric artery (SMA). Data were extracted including participant characteristics, frequency, intensity, timing and type of exercise and the effect on SMA flow. The quality of each study was assessed using the Downs and Black checklist.

Results

Sixteen studies, comprising 305 participants in total, were included. Methodological quality was generally poor. Healthy volunteers were used in twelve studies. SMA flow was found to be reduced in response to exercise in twelve studies, increased in one and unchanged in two studies. Clinical heterogeneity precluded a meta-analysis.

Conclusion

The weight of evidence suggests that superior mesenteric arterial flow is reduced immediately following exercise. Differences in frequency, intensity, timing and type of exercise make a consensus difficult. Further studies are warranted to provide a definitive understanding of the impact of exercise on mesenteric flow.

Text
10.1007_s10151-017-1589-9 - Version of Record
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More information

Accepted/In Press date: 11 January 2017
e-pub ahead of print date: 27 February 2017
Published date: March 2017

Identifiers

Local EPrints ID: 416124
URI: http://eprints.soton.ac.uk/id/eprint/416124
ISSN: 1123-6337
PURE UUID: 2c817ff0-ec5f-428f-8a5e-5a24f108ed3d
ORCID for Malcolm West: ORCID iD orcid.org/0000-0002-0345-5356

Catalogue record

Date deposited: 05 Dec 2017 17:30
Last modified: 16 Mar 2024 04:29

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Contributors

Author: Katherina Knight
Author: Susan Moug
Author: Malcolm West ORCID iD

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