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A subarachnoid haemorrhage-specific outcome tool

A subarachnoid haemorrhage-specific outcome tool
A subarachnoid haemorrhage-specific outcome tool
Functional outcome after subarachnoid haemorrhage (SAH) has traditionally been assessed using scales developed for other neurological conditions. The modified Rankin score (mRS) and Glasgow Outcome Scale (GOS) are most commonly used. Employment of these scales in SAH is hampered by well-recognised limitations. We set out to develop and validate a new condition-specific SAH Outcome Tool (SAHOT). Items addressing diverse aspects of the impact of SAH were collected during focus groups involving patients, next-of-kin and multidisciplinary professionals involved in SAH management. After a series of iterative revisions, the resultant questionnaire was applied to patients and their next-of-kin at one, three and six months post-SAH. Rasch methodology was utilized to finalize the structure of the questionnaire and explore the extent to which SAHOT scores met Rasch-based criteria of successful measurement. The SAHOT was further assessed using traditional scale evaluation techniques, and validated in a second separate SAH patient cohort. The final SAHOT included 56 items dealing with cognitive, physical, and behavioural/psychological consequences of SAH. Rasch analysis indicated the scale successfully measured functional outcome post-SAH. Three item scoring categories produced the best scale performance. There was no evidence of differential item functioning between patients and next-of-kin. The SAHOT was found to be acceptable, have good convergent and divergent validity, good discrimination and excellent responsiveness. It was successfully validated in a second SAH patient cohort. The SAHOT offers the first SAH-specific scientifically robust outcome measure with potential utility in neurovascular clinical services and research studies.
0006-8950
1111-1121
Pace, Adrian
0279b6ab-b7bf-44ec-a907-91fb06e70b00
Mitchell, Sophie
9fdadc95-b97d-4fb3-be76-c847d1418932
Casselden, Elizabeth
55ccf631-08b2-4e0b-b37c-014738ca4437
Zolnourian, Ardalan
5e8d4881-cdfd-4cb1-8eae-b98b13104648
Glazier, James
cd25b20a-e5b6-4697-89cc-6ee8930b8e6d
Foulkes, Lesley
ca340e7e-e79a-456d-959f-17c792dd233b
Bulters, Diederik
d6f9644a-a32f-45d8-b5ed-be54486ec21d
Galea, Ian
66209a2f-f7e6-4d63-afe4-e9299f156f0b
Pace, Adrian
0279b6ab-b7bf-44ec-a907-91fb06e70b00
Mitchell, Sophie
9fdadc95-b97d-4fb3-be76-c847d1418932
Casselden, Elizabeth
55ccf631-08b2-4e0b-b37c-014738ca4437
Zolnourian, Ardalan
5e8d4881-cdfd-4cb1-8eae-b98b13104648
Glazier, James
cd25b20a-e5b6-4697-89cc-6ee8930b8e6d
Foulkes, Lesley
ca340e7e-e79a-456d-959f-17c792dd233b
Bulters, Diederik
d6f9644a-a32f-45d8-b5ed-be54486ec21d
Galea, Ian
66209a2f-f7e6-4d63-afe4-e9299f156f0b

Pace, Adrian, Mitchell, Sophie, Casselden, Elizabeth, Zolnourian, Ardalan, Glazier, James, Foulkes, Lesley, Bulters, Diederik and Galea, Ian (2018) A subarachnoid haemorrhage-specific outcome tool. Brain, 141 (4), 1111-1121. (doi:10.1093/brain/awy003).

Record type: Article

Abstract

Functional outcome after subarachnoid haemorrhage (SAH) has traditionally been assessed using scales developed for other neurological conditions. The modified Rankin score (mRS) and Glasgow Outcome Scale (GOS) are most commonly used. Employment of these scales in SAH is hampered by well-recognised limitations. We set out to develop and validate a new condition-specific SAH Outcome Tool (SAHOT). Items addressing diverse aspects of the impact of SAH were collected during focus groups involving patients, next-of-kin and multidisciplinary professionals involved in SAH management. After a series of iterative revisions, the resultant questionnaire was applied to patients and their next-of-kin at one, three and six months post-SAH. Rasch methodology was utilized to finalize the structure of the questionnaire and explore the extent to which SAHOT scores met Rasch-based criteria of successful measurement. The SAHOT was further assessed using traditional scale evaluation techniques, and validated in a second separate SAH patient cohort. The final SAHOT included 56 items dealing with cognitive, physical, and behavioural/psychological consequences of SAH. Rasch analysis indicated the scale successfully measured functional outcome post-SAH. Three item scoring categories produced the best scale performance. There was no evidence of differential item functioning between patients and next-of-kin. The SAHOT was found to be acceptable, have good convergent and divergent validity, good discrimination and excellent responsiveness. It was successfully validated in a second SAH patient cohort. The SAHOT offers the first SAH-specific scientifically robust outcome measure with potential utility in neurovascular clinical services and research studies.

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Pace et al 2018_postprint - Accepted Manuscript
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SAHOT: SubArachnoid Haemorrhage Outcome Tool
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Pace et al 2018 supplement
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More information

Accepted/In Press date: 23 November 2017
e-pub ahead of print date: 1 February 2018
Published date: 1 April 2018

Identifiers

Local EPrints ID: 416152
URI: http://eprints.soton.ac.uk/id/eprint/416152
ISSN: 0006-8950
PURE UUID: 5fddfd11-eea7-446e-a155-974782c9defe
ORCID for Ian Galea: ORCID iD orcid.org/0000-0002-1268-5102

Catalogue record

Date deposited: 06 Dec 2017 17:30
Last modified: 26 Nov 2021 06:23

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Contributors

Author: Adrian Pace
Author: Sophie Mitchell
Author: Elizabeth Casselden
Author: Ardalan Zolnourian
Author: James Glazier
Author: Lesley Foulkes
Author: Diederik Bulters
Author: Ian Galea ORCID iD

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