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Guidelines on the management of abnormal liver blood tests

Guidelines on the management of abnormal liver blood tests
Guidelines on the management of abnormal liver blood tests

These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines, which this document supersedes, were written in 2000 and have undergone extensive revision by members of the Guidelines Development Group (GDG). The GDG comprises representatives from patient/carer groups (British Liver Trust, Liver4life, PBC Foundation and PSC Support), elected members of the BSG liver section (including representatives from Scotland and Wales), British Association for the Study of the Liver (BASL), Specialist Advisory Committee in Clinical Biochemistry/Royal College of Pathology and Association for Clinical Biochemistry, British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN), Public Health England (implementation and screening), Royal College of General Practice, British Society of Gastrointestinal and Abdominal Radiologists (BSGAR) and Society of Acute Medicine. The quality of evidence and grading of recommendations was appraised using the AGREE II tool. These guidelines deal specifically with the management of abnormal liver blood tests in children and adults in both primary and secondary care under the following subheadings: (1) What constitutes an abnormal liver blood test? (2) What constitutes a standard liver blood test panel? (3) When should liver blood tests be checked? (4) Does the extent and duration of abnormal liver blood tests determine subsequent investigation? (5) Response to abnormal liver blood tests. They are not designed to deal with the management of the underlying liver disease.

alcoholic liver disease, fibrosis, liver, nonalcoholic steatohepatitis
1468-3288
6-19
Newsome, Philip N.
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Cramb, Rob
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Davison, Suzanne M.
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Dillon, John F.
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Foulerton, Mark
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Godfrey, Edmund M.
af9a51d4-8fc7-4595-a3ca-54aef6b155ac
Hall, Richard
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Harrower, Ulrike
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Hudson, Mark
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Langford, Andrew
78d75bf8-e0ad-49ba-bd04-8a91815a837a
Mackie, Anne
003b85c2-e1eb-44cb-95a9-303afa54bcd3
Mitchell-Thain, Robert
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Sennett, Karen
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Sheron, Nicholas C.
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Verne, Julia
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Walmsley, Martine
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Yeoman, Andrew
d2ca8663-cf25-46c7-b69a-82071614872b
Newsome, Philip N.
434e6113-6c44-4a9f-b5e8-60649965b063
Cramb, Rob
ee537a83-1c72-4eef-93d6-52124a55f5c6
Davison, Suzanne M.
45a0aaf8-093f-4ed7-a74a-a853aade57f9
Dillon, John F.
20705ee1-dc06-4334-8e1a-60fc7fb5bf1d
Foulerton, Mark
67fb2984-19e0-47a0-907f-8d97ac4bab6c
Godfrey, Edmund M.
af9a51d4-8fc7-4595-a3ca-54aef6b155ac
Hall, Richard
da2f3396-402c-410e-a0db-dc04abc01e56
Harrower, Ulrike
4af688ab-75cc-423a-88f0-cb0d6c9e6c98
Hudson, Mark
0e9865f4-d845-4f88-8030-d717baf5f7eb
Langford, Andrew
78d75bf8-e0ad-49ba-bd04-8a91815a837a
Mackie, Anne
003b85c2-e1eb-44cb-95a9-303afa54bcd3
Mitchell-Thain, Robert
6d19eb4f-06ae-4720-ae4b-83ba550d63fb
Sennett, Karen
d295e314-5a5e-4d01-8090-6738fc759443
Sheron, Nicholas C.
cbf852e3-cfaa-43b2-ab99-a954d96069f1
Verne, Julia
46bddbb7-44f2-4928-a2a6-b6fbefd8b14a
Walmsley, Martine
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Yeoman, Andrew
d2ca8663-cf25-46c7-b69a-82071614872b

Newsome, Philip N., Cramb, Rob, Davison, Suzanne M., Dillon, John F., Foulerton, Mark, Godfrey, Edmund M., Hall, Richard, Harrower, Ulrike, Hudson, Mark, Langford, Andrew, Mackie, Anne, Mitchell-Thain, Robert, Sennett, Karen, Sheron, Nicholas C., Verne, Julia, Walmsley, Martine and Yeoman, Andrew (2018) Guidelines on the management of abnormal liver blood tests. Gut, 67 (1), 6-19. (doi:10.1136/gutjnl-2017-314924).

Record type: Article

Abstract

These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines, which this document supersedes, were written in 2000 and have undergone extensive revision by members of the Guidelines Development Group (GDG). The GDG comprises representatives from patient/carer groups (British Liver Trust, Liver4life, PBC Foundation and PSC Support), elected members of the BSG liver section (including representatives from Scotland and Wales), British Association for the Study of the Liver (BASL), Specialist Advisory Committee in Clinical Biochemistry/Royal College of Pathology and Association for Clinical Biochemistry, British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN), Public Health England (implementation and screening), Royal College of General Practice, British Society of Gastrointestinal and Abdominal Radiologists (BSGAR) and Society of Acute Medicine. The quality of evidence and grading of recommendations was appraised using the AGREE II tool. These guidelines deal specifically with the management of abnormal liver blood tests in children and adults in both primary and secondary care under the following subheadings: (1) What constitutes an abnormal liver blood test? (2) What constitutes a standard liver blood test panel? (3) When should liver blood tests be checked? (4) Does the extent and duration of abnormal liver blood tests determine subsequent investigation? (5) Response to abnormal liver blood tests. They are not designed to deal with the management of the underlying liver disease.

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Accepted/In Press date: 15 October 2017
e-pub ahead of print date: 9 November 2017
Published date: 1 January 2018
Keywords: alcoholic liver disease, fibrosis, liver, nonalcoholic steatohepatitis

Identifiers

Local EPrints ID: 417328
URI: https://eprints.soton.ac.uk/id/eprint/417328
ISSN: 1468-3288
PURE UUID: 3ceb92d2-7a07-4011-933d-5ebc4baf4350
ORCID for Nicholas C. Sheron: ORCID iD orcid.org/0000-0001-5232-8292

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Date deposited: 30 Jan 2018 17:30
Last modified: 24 May 2018 16:31

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Contributors

Author: Philip N. Newsome
Author: Rob Cramb
Author: Suzanne M. Davison
Author: John F. Dillon
Author: Mark Foulerton
Author: Edmund M. Godfrey
Author: Richard Hall
Author: Ulrike Harrower
Author: Mark Hudson
Author: Andrew Langford
Author: Anne Mackie
Author: Robert Mitchell-Thain
Author: Karen Sennett
Author: Julia Verne
Author: Martine Walmsley
Author: Andrew Yeoman

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