The University of Southampton
University of Southampton Institutional Repository

Is the rate of revision of 36 mm metal-on-metal total hip arthroplasties with Pinnacle acetabular components related to the year of the initial operation? An interrupted time-series analysis using data from the national joint registry for England and Wales

Is the rate of revision of 36 mm metal-on-metal total hip arthroplasties with Pinnacle acetabular components related to the year of the initial operation? An interrupted time-series analysis using data from the national joint registry for England and Wales
Is the rate of revision of 36 mm metal-on-metal total hip arthroplasties with Pinnacle acetabular components related to the year of the initial operation? An interrupted time-series analysis using data from the national joint registry for England and Wales

Aims The aim of this study was to determine whether the rates of revision for metal-on-metal (MoM) total hip arthroplasties (THAs) with Pinnacle components varied according to the year of the initial operation, and compare these with the rates of revision for other designs of MoM THA. Patients and Methods Data from the National Joint Registry for England and Wales included 36 mm MoM THAs with Pinnacle acetabular components which were undertaken between 2003 and 2012 with follow-up for at least five years (n = 10 776) and a control group of other MoM THAs (n = 13 817). The effect of the year of the primary operation on all-cause rates of revision was assessed using Cox regression and interrupted time-series analysis. Results For MoM THAs involving Pinnacle components, those undertaken between 2007 and 2012 had higher rates of revision compared with those undertaken between 2004 and 2006 (hazard ratio (HR) 2.01; 95% confidence interval (CI) 1.57 to 2.57; p < 0.001). For THAs undertaken during and after 2007, the number of revisions per 1000 implant-years at risk significantly increased by 5.20 (95% CI 0.52 to 9.89; p = 0.033) compared with those undertaken before this time. In the control group, THAs undertaken between 2007 and 2012 also had higher rates of revision (HR 1.77; 95% CI 1.49 to 2.10; p < 0.001), with revisions per 1000 implant-years for those undertaken during and after 2007 significantly increasing by 6.13 (95% CI 1.42 to 10.83; p = 0.016). Conclusion The five-year revision rates were significantly increased for all primary MoM THAs undertaken from 2007 onwards. Contrary to recent reports, this finding was not specific to those involving Pinnacle acetabular components and may be explained by increased surveillance and recent lowering of the threshold for revision.

2049-4394
33-41
Matharu, G. S.
ff0c3613-eb2c-41ee-8873-1f3d309ee494
Hunt, L. P.
79158781-3328-4cad-9736-315b9c4cb739
Murray, D.W.
8b9e5879-3fa7-4e4a-98a9-e0f11dcb2462
Howard, P.
6dbf8257-8cbd-4df9-bab1-34975e0cd8cd
Pandit, H. G.
786468fe-77e9-4bc9-996d-74c173e882d6
Blom, A. W.
1faf6ee2-001c-4896-b072-c4023408271e
Bolland, B.
7fbd3d12-b311-4570-8aee-fc0a8219b41a
Judge, A.
c6a83964-1d7c-4aa8-b2bf-9c264d1e487d
Matharu, G. S.
ff0c3613-eb2c-41ee-8873-1f3d309ee494
Hunt, L. P.
79158781-3328-4cad-9736-315b9c4cb739
Murray, D.W.
8b9e5879-3fa7-4e4a-98a9-e0f11dcb2462
Howard, P.
6dbf8257-8cbd-4df9-bab1-34975e0cd8cd
Pandit, H. G.
786468fe-77e9-4bc9-996d-74c173e882d6
Blom, A. W.
1faf6ee2-001c-4896-b072-c4023408271e
Bolland, B.
7fbd3d12-b311-4570-8aee-fc0a8219b41a
Judge, A.
c6a83964-1d7c-4aa8-b2bf-9c264d1e487d

Matharu, G. S., Hunt, L. P., Murray, D.W., Howard, P., Pandit, H. G., Blom, A. W., Bolland, B. and Judge, A. (2018) Is the rate of revision of 36 mm metal-on-metal total hip arthroplasties with Pinnacle acetabular components related to the year of the initial operation? An interrupted time-series analysis using data from the national joint registry for England and Wales. Bone and Joint Journal, 100B (1), 33-41. (doi:10.1302/0301-620X.100B1.BJJ-2017-0625.R2).

Record type: Article

Abstract

Aims The aim of this study was to determine whether the rates of revision for metal-on-metal (MoM) total hip arthroplasties (THAs) with Pinnacle components varied according to the year of the initial operation, and compare these with the rates of revision for other designs of MoM THA. Patients and Methods Data from the National Joint Registry for England and Wales included 36 mm MoM THAs with Pinnacle acetabular components which were undertaken between 2003 and 2012 with follow-up for at least five years (n = 10 776) and a control group of other MoM THAs (n = 13 817). The effect of the year of the primary operation on all-cause rates of revision was assessed using Cox regression and interrupted time-series analysis. Results For MoM THAs involving Pinnacle components, those undertaken between 2007 and 2012 had higher rates of revision compared with those undertaken between 2004 and 2006 (hazard ratio (HR) 2.01; 95% confidence interval (CI) 1.57 to 2.57; p < 0.001). For THAs undertaken during and after 2007, the number of revisions per 1000 implant-years at risk significantly increased by 5.20 (95% CI 0.52 to 9.89; p = 0.033) compared with those undertaken before this time. In the control group, THAs undertaken between 2007 and 2012 also had higher rates of revision (HR 1.77; 95% CI 1.49 to 2.10; p < 0.001), with revisions per 1000 implant-years for those undertaken during and after 2007 significantly increasing by 6.13 (95% CI 1.42 to 10.83; p = 0.016). Conclusion The five-year revision rates were significantly increased for all primary MoM THAs undertaken from 2007 onwards. Contrary to recent reports, this finding was not specific to those involving Pinnacle acetabular components and may be explained by increased surveillance and recent lowering of the threshold for revision.

This record has no associated files available for download.

More information

Published date: 5 January 2018

Identifiers

Local EPrints ID: 417534
URI: http://eprints.soton.ac.uk/id/eprint/417534
ISSN: 2049-4394
PURE UUID: f0a114d4-624c-426c-87ff-a01bcf058974

Catalogue record

Date deposited: 02 Feb 2018 17:30
Last modified: 15 Mar 2024 18:13

Export record

Altmetrics

Contributors

Author: G. S. Matharu
Author: L. P. Hunt
Author: D.W. Murray
Author: P. Howard
Author: H. G. Pandit
Author: A. W. Blom
Author: B. Bolland
Author: A. Judge

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×