CrossTalk opposing view: dynamic cerebral autoregulation should be quantified using induced (rather than spontaneous) blood pressure fluctuations
CrossTalk opposing view: dynamic cerebral autoregulation should be quantified using induced (rather than spontaneous) blood pressure fluctuations
Suppose you want to take a car for a test drive. You prefer a smooth ride, so you are probably particularly interested in the car’s suspension system. Where do you take your car? Will you take it for a ride on a well-maintained highway, or will you select worn-down roads with cobblestones, potholes and speed bumps? The answer is clear: you can’t test the car’s suspension system if you don’t challenge it. Now imagine cerebral autoregulation (CA) as our brain’s suspension system, dampening out fluctuations in blood flow as blood pressure varies.
blood pressure, cerebral blood flow, cerebral circulation
7-9
Simpson, David
53674880-f381-4cc9-8505-6a97eeac3c2a
Claassen, Jurgen
a9f02f02-831d-47bb-897e-670cbba44016
1 January 2018
Simpson, David
53674880-f381-4cc9-8505-6a97eeac3c2a
Claassen, Jurgen
a9f02f02-831d-47bb-897e-670cbba44016
Simpson, David and Claassen, Jurgen
(2018)
CrossTalk opposing view: dynamic cerebral autoregulation should be quantified using induced (rather than spontaneous) blood pressure fluctuations.
Journal of Physiology, 596 (1), .
(doi:10.1113/JP273900).
Abstract
Suppose you want to take a car for a test drive. You prefer a smooth ride, so you are probably particularly interested in the car’s suspension system. Where do you take your car? Will you take it for a ride on a well-maintained highway, or will you select worn-down roads with cobblestones, potholes and speed bumps? The answer is clear: you can’t test the car’s suspension system if you don’t challenge it. Now imagine cerebral autoregulation (CA) as our brain’s suspension system, dampening out fluctuations in blood flow as blood pressure varies.
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Simpson_et_al-2018-The_Journal_of_Physiology
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e-pub ahead of print date: 5 December 2017
Published date: 1 January 2018
Keywords:
blood pressure, cerebral blood flow, cerebral circulation
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Local EPrints ID: 417648
URI: http://eprints.soton.ac.uk/id/eprint/417648
ISSN: 0022-3751
PURE UUID: 50bf97f7-7045-4427-aed7-115b27a45588
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Date deposited: 08 Feb 2018 17:30
Last modified: 16 Mar 2024 03:29
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Author:
Jurgen Claassen
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