Sleep in adults with ADHD: systematic review and meta-analysis of subjective and objective studies
Sleep in adults with ADHD: systematic review and meta-analysis of subjective and objective studies
Sleep alterations associated with adulthood ADHD are poorly understood. Here, we conducted the first meta-analysis of sleep studies in adults with ADHD. Based on a pre-registered protocol (PROSPERO-CRD42017065407), we searched Pubmed, Ovid and Web of Knowledge databases through August 3rd, 2017, with no language or publication type restrictions, and contacted study authors for unpublished data/information. From a pool of 8,812 references, we retained 13 studies. Random-effects models were performed and study quality was rated using the Newcastle-Ottawa Scale. Compared to adults without ADHD, those with ADHD significantly differed in seven out of nine subjective parameters (Standardized Mean Difference, SMD, ranging from 0.56 to 1.55) and two out of five actigraphic parameters [SMD (95% CI): sleep onset latency: 0.80 (0.46-1.14); sleep efficiency: -0.68 (-1.03, -0.34)]. No significant differences were detected for polysomnographic parameters. We conclude that, whereas subjectively reported sleep problems are significantly associated with ADHD in adults and should be systematically screened during the clinical interview, additional research is needed to understand if they are underpinned by objective sleep alterations.
61-71
Diaz Roman, Amparo
47ad1105-3105-4a04-a4d1-f17eb8a36596
Mitchell, Raziya
e070a965-f581-4418-8b07-4b20a78fd793
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
June 2018
Diaz Roman, Amparo
47ad1105-3105-4a04-a4d1-f17eb8a36596
Mitchell, Raziya
e070a965-f581-4418-8b07-4b20a78fd793
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Diaz Roman, Amparo, Mitchell, Raziya and Cortese, Samuele
(2018)
Sleep in adults with ADHD: systematic review and meta-analysis of subjective and objective studies.
Neuroscience & Biobehavioral Reviews, 89, .
(doi:10.1016/j.neubiorev.2018.02.014).
Abstract
Sleep alterations associated with adulthood ADHD are poorly understood. Here, we conducted the first meta-analysis of sleep studies in adults with ADHD. Based on a pre-registered protocol (PROSPERO-CRD42017065407), we searched Pubmed, Ovid and Web of Knowledge databases through August 3rd, 2017, with no language or publication type restrictions, and contacted study authors for unpublished data/information. From a pool of 8,812 references, we retained 13 studies. Random-effects models were performed and study quality was rated using the Newcastle-Ottawa Scale. Compared to adults without ADHD, those with ADHD significantly differed in seven out of nine subjective parameters (Standardized Mean Difference, SMD, ranging from 0.56 to 1.55) and two out of five actigraphic parameters [SMD (95% CI): sleep onset latency: 0.80 (0.46-1.14); sleep efficiency: -0.68 (-1.03, -0.34)]. No significant differences were detected for polysomnographic parameters. We conclude that, whereas subjectively reported sleep problems are significantly associated with ADHD in adults and should be systematically screened during the clinical interview, additional research is needed to understand if they are underpinned by objective sleep alterations.
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Submitted date: 2 February 2018
Accepted/In Press date: 19 February 2018
e-pub ahead of print date: 2 March 2018
Published date: June 2018
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Local EPrints ID: 418332
URI: http://eprints.soton.ac.uk/id/eprint/418332
ISSN: 0149-7634
PURE UUID: fdaa3109-2561-492d-b96e-935159a7d4ff
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Date deposited: 28 Feb 2018 17:30
Last modified: 16 Mar 2024 06:14
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Author:
Amparo Diaz Roman
Author:
Raziya Mitchell
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