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Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study

Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study
Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study
Purpose: we determined the efficacy and safety of flexible ureterorenoscopy for single intrarenal calculi and further stratified efficacy by stone burden.Materials and Methods: CROES collected prospective data on consecutive patients with urinary stones treated with ureterorenoscopy at 114 centers worldwide for 1 year. Only patients who underwent flexible ureterorenoscopy for a solitary renal stone were included in study. Preoperative and intraoperative characteristics, and postoperative outcomes were evaluated. Relationships between stone size and the stone-free rate, operative time, complications, hospital stay and need for re-treatment were determined.Results: a total of 1,210 patients with a solitary kidney stone less than 10 (52.2%), 10 to 20 (43.2%) and greater than 20 mm (4.6%) were treated with flexible ureterorenoscopy. The stone-free rate negatively correlated with stone size when adjusted for body mass index. Operative time positively correlated with stone size when adjusted for body mass index. The single session stone-free rate was 90% and 80% for stones less than 10 and less than 15 mm, respectively. Patients with stones greater than 20 mm achieved a 30% stone-free rate, more often needed re-treatment and were more often rehospitalized. There was no difference in the overall complication rate by stone size. However, patients with a stone greater than 20 mm showed a higher probability of fever after flexible ureterorenoscopy than those with a smaller stone.Conclusions: our data indicate that flexible ureterorenoscopy for a single intrarenal stone is a safe procedure. Best results after single session flexible ureterorenoscopy were obtained for stones less than 15 mm.
Humans, Kidney Calculi, Prospective Studies, Treatment Outcome, Ureteroscopy, Evaluation Studies, Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't
0022-5347
137-143
Skolarikos, Andreas
7308ae8f-62d1-4ce6-9e66-d8c4c80294ad
Gross, Andreas J
01faec9e-9039-4229-8f3a-693e37bbbf8e
Krebs, Alfred
d43aa551-acce-44d2-9af1-4c8c049a1bd4
Unal, Dogan
ff749bac-9d53-4c8d-84bc-faa0b3147084
Bercowsky, Eduardo
e4f50411-e022-4f65-bf4e-98454382ae54
Eltahawy, Ehab
53b79757-4aaf-48c9-b09a-a9749c9f307b
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
de la Rosette, Jean
16ebd10e-bcc9-48e8-a433-212aa88f310f
Skolarikos, Andreas
7308ae8f-62d1-4ce6-9e66-d8c4c80294ad
Gross, Andreas J
01faec9e-9039-4229-8f3a-693e37bbbf8e
Krebs, Alfred
d43aa551-acce-44d2-9af1-4c8c049a1bd4
Unal, Dogan
ff749bac-9d53-4c8d-84bc-faa0b3147084
Bercowsky, Eduardo
e4f50411-e022-4f65-bf4e-98454382ae54
Eltahawy, Ehab
53b79757-4aaf-48c9-b09a-a9749c9f307b
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
de la Rosette, Jean
16ebd10e-bcc9-48e8-a433-212aa88f310f

Skolarikos, Andreas, Gross, Andreas J, Krebs, Alfred, Unal, Dogan, Bercowsky, Eduardo, Eltahawy, Ehab, Somani, Bhaskar and de la Rosette, Jean (2015) Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study. The Journal of Urology, 194 (1), 137-143. (doi:10.1016/j.juro.2015.01.112).

Record type: Article

Abstract

Purpose: we determined the efficacy and safety of flexible ureterorenoscopy for single intrarenal calculi and further stratified efficacy by stone burden.Materials and Methods: CROES collected prospective data on consecutive patients with urinary stones treated with ureterorenoscopy at 114 centers worldwide for 1 year. Only patients who underwent flexible ureterorenoscopy for a solitary renal stone were included in study. Preoperative and intraoperative characteristics, and postoperative outcomes were evaluated. Relationships between stone size and the stone-free rate, operative time, complications, hospital stay and need for re-treatment were determined.Results: a total of 1,210 patients with a solitary kidney stone less than 10 (52.2%), 10 to 20 (43.2%) and greater than 20 mm (4.6%) were treated with flexible ureterorenoscopy. The stone-free rate negatively correlated with stone size when adjusted for body mass index. Operative time positively correlated with stone size when adjusted for body mass index. The single session stone-free rate was 90% and 80% for stones less than 10 and less than 15 mm, respectively. Patients with stones greater than 20 mm achieved a 30% stone-free rate, more often needed re-treatment and were more often rehospitalized. There was no difference in the overall complication rate by stone size. However, patients with a stone greater than 20 mm showed a higher probability of fever after flexible ureterorenoscopy than those with a smaller stone.Conclusions: our data indicate that flexible ureterorenoscopy for a single intrarenal stone is a safe procedure. Best results after single session flexible ureterorenoscopy were obtained for stones less than 15 mm.

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More information

Published date: July 2015
Keywords: Humans, Kidney Calculi, Prospective Studies, Treatment Outcome, Ureteroscopy, Evaluation Studies, Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't

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Local EPrints ID: 419122
URI: http://eprints.soton.ac.uk/id/eprint/419122
ISSN: 0022-5347
PURE UUID: 0586ec5d-0f86-462d-9132-cba61859a1d6

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Date deposited: 05 Apr 2018 16:30
Last modified: 09 Sep 2020 16:32

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