Towards the shell biorefinery: sustainable synthesis of the anticancer alkaloid Proximicin A from chitin

Sadiq, Alejandro D., Chen, Xi, Yan, Ning and Sperry, Jonathan (2018) Towards the shell biorefinery: sustainable synthesis of the anticancer alkaloid Proximicin A from chitin. ChemSusChem, 11 (3), 532-535. (doi:10.1002/cssc.201702356).

Record type: Article

Abstract

A shell biorefinery would involve fractionation of crustacean shells and incorporation of the components into value-added products, particularly those that contain nitrogen. In a proof-of-concept study that validates this concept, the anticancer alkaloid proximicin A has been synthesized from the chitin-derived platform chemical 3-acetamido-5-acetylfuran (3A5AF). This study accentuates the leading role chitin is likely to play in the sustainable production of nitrogen-containing fine chemicals that are not directly attainable from lignocellulose.

This record has no associated files available for download.

More information

e-pub ahead of print date: 5 January 2018

Published date: 9 February 2018

Keywords: alkaloids, biomass, cancer, shell biorefinery, sustainable synthesis

Learn more about Chemistry research

Identifiers

Local EPrints ID: 419181

URI: http://eprints.soton.ac.uk/id/eprint/419181

DOI: doi:10.1002/cssc.201702356

ISSN: 1864-5631

PURE UUID: 17bdf0c0-a2ec-4b31-a70e-eb5e1a6f421f

Catalogue record

Date deposited: 06 Apr 2018 16:30

Last modified: 05 Jun 2024 17:32

Export record

Altmetrics

Share this record

Share this on Facebook Share this on Twitter Share this on Weibo

Contributors

Author: Alejandro D. Sadiq

Author: Xi Chen

Author: Ning Yan

Author: Jonathan Sperry

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Library staff additional information