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The effects of electroporation on skin impedance

The effects of electroporation on skin impedance
The effects of electroporation on skin impedance

Electroporation is the creation of pores in a cell by applying an external electrical field and creating a voltage in the range of 200 mV-1 V across the cell's membrane. This process is used intentionally in order to introduce chemicals, drugs or DNA into a cell. A model was created to determine whether electroporation would occur during the use of the signals typically used during functional electrical stimulation of skin and if it occurs what effect it has on the overall impedance of skin. Results from the simulation show that there is a threefold reduction in the electrical impedance of the cells.

electroporation, skin impedance, skin modelling
Davies, Luke
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Chappell, Paul
2d2ec52b-e5d0-4c36-ac20-0a86589a880e
Davies, Luke
3b12e757-daa0-4f35-bdcf-9281baad3558
Chappell, Paul
2d2ec52b-e5d0-4c36-ac20-0a86589a880e

Davies, Luke and Chappell, Paul (2018) The effects of electroporation on skin impedance. Biomedical Physics & Engineering Express, 4 (2). (doi:10.1088/2057-1976/aa9d72).

Record type: Article

Abstract

Electroporation is the creation of pores in a cell by applying an external electrical field and creating a voltage in the range of 200 mV-1 V across the cell's membrane. This process is used intentionally in order to introduce chemicals, drugs or DNA into a cell. A model was created to determine whether electroporation would occur during the use of the signals typically used during functional electrical stimulation of skin and if it occurs what effect it has on the overall impedance of skin. Results from the simulation show that there is a threefold reduction in the electrical impedance of the cells.

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The effects of Electroporation on Skin Impedance - Accepted Manuscript
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Accepted/In Press date: 27 November 2017
e-pub ahead of print date: 18 January 2018
Published date: 1 March 2018
Keywords: electroporation, skin impedance, skin modelling

Identifiers

Local EPrints ID: 419358
URI: https://eprints.soton.ac.uk/id/eprint/419358
PURE UUID: c72564de-c2ed-4357-88c2-1096324a5e2d

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Date deposited: 11 Apr 2018 16:30
Last modified: 14 Mar 2019 05:10

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Contributors

Author: Luke Davies
Author: Paul Chappell

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