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Is cryotherapy a genuine rival to robotic assisted partial nephrectomy in the management of suspected renal malignancy?: A systematic review and meta-analysis

Is cryotherapy a genuine rival to robotic assisted partial nephrectomy in the management of suspected renal malignancy?: A systematic review and meta-analysis
Is cryotherapy a genuine rival to robotic assisted partial nephrectomy in the management of suspected renal malignancy?: A systematic review and meta-analysis

We systematically reviewed world literature and compare oncological outcomes, morbidity, renal function and peri-operative outcome between cryotherapy (CA) and robotic assisted partial nephrectomy (RAPN) for suspected renal malignancy. There was a statistically significant difference for "recurrence rates" between the 2 techniques, favouring the RAPN cohort. There was no statistically significant difference in overall and ≥Clavien 3a complication rates between the 2 techniques. The quality of evidence for recurrence rates, overall complication and ≥Clavien 3a were 'moderate', 'low' and 'very low' respectively on GRADE approach. If a nephron sparing approach is indicated, RAPN should be the approach of choice.

Journal Article, Review
0090-4295
6-11
Rai, Bhavan Prasad
e1156207-bfd1-4f89-b0aa-9e55fc54235b
Jones, Patrick
d27beb5b-0e09-4ed5-89f0-6c62421c2397
Tait, Campbell
b8803f3a-de2a-4926-bc90-374443689e9a
Amitharaj, Ramachandran
cc608c63-9d11-4eed-a396-4db055ed1102
Gowda, Raj
705d56d2-2dd4-4b08-bb1b-afa25ad70ded
Bhatti, Aftab
67a25b27-ff6e-461e-a436-41a1e52d56e6
Adshead, Jim
d40d8f38-f725-4ebc-95ab-a2bc0f8a157d
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
Rai, Bhavan Prasad
e1156207-bfd1-4f89-b0aa-9e55fc54235b
Jones, Patrick
d27beb5b-0e09-4ed5-89f0-6c62421c2397
Tait, Campbell
b8803f3a-de2a-4926-bc90-374443689e9a
Amitharaj, Ramachandran
cc608c63-9d11-4eed-a396-4db055ed1102
Gowda, Raj
705d56d2-2dd4-4b08-bb1b-afa25ad70ded
Bhatti, Aftab
67a25b27-ff6e-461e-a436-41a1e52d56e6
Adshead, Jim
d40d8f38-f725-4ebc-95ab-a2bc0f8a157d
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9

Rai, Bhavan Prasad, Jones, Patrick, Tait, Campbell, Amitharaj, Ramachandran, Gowda, Raj, Bhatti, Aftab, Adshead, Jim and Somani, Bhaskar (2018) Is cryotherapy a genuine rival to robotic assisted partial nephrectomy in the management of suspected renal malignancy?: A systematic review and meta-analysis. Urology, 118, 6-11. (doi:10.1016/j.urology.2017.09.008).

Record type: Review

Abstract

We systematically reviewed world literature and compare oncological outcomes, morbidity, renal function and peri-operative outcome between cryotherapy (CA) and robotic assisted partial nephrectomy (RAPN) for suspected renal malignancy. There was a statistically significant difference for "recurrence rates" between the 2 techniques, favouring the RAPN cohort. There was no statistically significant difference in overall and ≥Clavien 3a complication rates between the 2 techniques. The quality of evidence for recurrence rates, overall complication and ≥Clavien 3a were 'moderate', 'low' and 'very low' respectively on GRADE approach. If a nephron sparing approach is indicated, RAPN should be the approach of choice.

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Accepted/In Press date: 14 September 2017
e-pub ahead of print date: 28 September 2017
Published date: August 2018
Keywords: Journal Article, Review

Identifiers

Local EPrints ID: 419559
URI: http://eprints.soton.ac.uk/id/eprint/419559
ISSN: 0090-4295
PURE UUID: 01f4b40c-8b1a-44f4-8b07-6f4d756ee489

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Date deposited: 13 Apr 2018 16:30
Last modified: 15 Jan 2020 17:42

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