Nutritional outcomes in cystic fibrosis - are we doing enough?
Nutritional outcomes in cystic fibrosis - are we doing enough?
Although outcome data for individuals with cystic fibrosis (CF) have shown consistent improvements throughout the twentieth century, more recent national registry data suggests that outcomes have reached a plateau. Median values for nutritional outcomes in CF currently cluster around the fiftieth centile for the normal population. These data suggest that up to half of CF patients have sub-optimal body mass index (BMI) which might have a significant adverse impact on their respiratory status. BMI might be underestimating the extent to which more important lean body mass might also be reduced. Nutritional decline is a particular problem during adolescence and commonly persists into early adult life. Current treatment strategies to optimize nutrition include the use of high energy diets, proton pump inhibitors and optimal use of enzyme preparations including higher strength preparations to decrease pill burden. Whilst these are all of potential benefit, poor adherence to nutritional care recommendations is probably the greatest impediment to future health improvement. More effective strategies to impact on treatment adherence are needed.
Adherence, Body Mass Index, Cystic Fibrosis, Lean Body Mass, Nutrition
31-34
Connett, Gary J.
55d5676c-90d8-46bf-a508-62eded276516
Pike, Katharine C.
99a84385-a195-43f1-bd68-2af0af420c95
1 October 2015
Connett, Gary J.
55d5676c-90d8-46bf-a508-62eded276516
Pike, Katharine C.
99a84385-a195-43f1-bd68-2af0af420c95
Connett, Gary J. and Pike, Katharine C.
(2015)
Nutritional outcomes in cystic fibrosis - are we doing enough?
Paediatric Respiratory Reviews, 16 (Supplement 1), , [1062].
(doi:10.1016/j.prrv.2015.07.015).
Abstract
Although outcome data for individuals with cystic fibrosis (CF) have shown consistent improvements throughout the twentieth century, more recent national registry data suggests that outcomes have reached a plateau. Median values for nutritional outcomes in CF currently cluster around the fiftieth centile for the normal population. These data suggest that up to half of CF patients have sub-optimal body mass index (BMI) which might have a significant adverse impact on their respiratory status. BMI might be underestimating the extent to which more important lean body mass might also be reduced. Nutritional decline is a particular problem during adolescence and commonly persists into early adult life. Current treatment strategies to optimize nutrition include the use of high energy diets, proton pump inhibitors and optimal use of enzyme preparations including higher strength preparations to decrease pill burden. Whilst these are all of potential benefit, poor adherence to nutritional care recommendations is probably the greatest impediment to future health improvement. More effective strategies to impact on treatment adherence are needed.
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e-pub ahead of print date: 22 September 2015
Published date: 1 October 2015
Keywords:
Adherence, Body Mass Index, Cystic Fibrosis, Lean Body Mass, Nutrition
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Local EPrints ID: 419580
URI: http://eprints.soton.ac.uk/id/eprint/419580
ISSN: 1526-0542
PURE UUID: 17d40e88-b817-44f6-99d0-1bed2052c341
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Date deposited: 13 Apr 2018 16:30
Last modified: 16 Mar 2024 04:35
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Author:
Gary J. Connett
Author:
Katharine C. Pike
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