A Quasi-Concertina force-displacement MEMS probe for measuring biomechanical properties
A Quasi-Concertina force-displacement MEMS probe for measuring biomechanical properties
In this work the development of a novel Quasi-Concertina (QC) microelectromechanical systems (MEMS) force - displacement (F-D) sensor is presented. The developed sensor has a resolution as small as 5.6 nN and 1.25 nm and a range of as much as 5.5 mN and 1000 μm. The performance of the microfabricated proof-of-concept QC MEMS device is in good agreement with our analytical and numerical estimates. Force sensors with these attributes will enable the mechanical properties of biological phenomena to be continuously measured over large F-D ranges without the need to change the measurement instrument. Thus, this sensor will appeal to biologists, biochemists, life scientists, clinicians, engineers, and physicist researchers working to understand the fundamentals of cell biology, the onset and progression of diseases such as cancer, and for the development of tools for the diagnostics, prophylactics and therapeutics of diseases.
67-74
Grech, David
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Tarazona, Antulio
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De Leon, Maria Theresa
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Kiang, Kian S.
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Zekonyte, Jurgita
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Wood, Robert J.K.
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Chong, Harold M.H.
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1 June 2018
Grech, David
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Tarazona, Antulio
c6ae87c5-c746-4f89-9ff0-9e7b6874e94f
De Leon, Maria Theresa
779b393c-38ac-47dd-b960-818eda45de2c
Kiang, Kian S.
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Zekonyte, Jurgita
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Wood, Robert J.K.
d9523d31-41a8-459a-8831-70e29ffe8a73
Chong, Harold M.H.
795aa67f-29e5-480f-b1bc-9bd5c0d558e1
Grech, David, Tarazona, Antulio, De Leon, Maria Theresa, Kiang, Kian S., Zekonyte, Jurgita, Wood, Robert J.K. and Chong, Harold M.H.
(2018)
A Quasi-Concertina force-displacement MEMS probe for measuring biomechanical properties.
Sensors and Actuators A: Physical, 275, .
(doi:10.1016/j.sna.2018.03.031).
Abstract
In this work the development of a novel Quasi-Concertina (QC) microelectromechanical systems (MEMS) force - displacement (F-D) sensor is presented. The developed sensor has a resolution as small as 5.6 nN and 1.25 nm and a range of as much as 5.5 mN and 1000 μm. The performance of the microfabricated proof-of-concept QC MEMS device is in good agreement with our analytical and numerical estimates. Force sensors with these attributes will enable the mechanical properties of biological phenomena to be continuously measured over large F-D ranges without the need to change the measurement instrument. Thus, this sensor will appeal to biologists, biochemists, life scientists, clinicians, engineers, and physicist researchers working to understand the fundamentals of cell biology, the onset and progression of diseases such as cancer, and for the development of tools for the diagnostics, prophylactics and therapeutics of diseases.
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Accepted/In Press date: 20 March 2018
e-pub ahead of print date: 28 March 2018
Published date: 1 June 2018
Identifiers
Local EPrints ID: 419804
URI: http://eprints.soton.ac.uk/id/eprint/419804
ISSN: 0924-4247
PURE UUID: 8030f04f-132a-4241-9dd2-692f1ba84d1f
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Date deposited: 20 Apr 2018 16:30
Last modified: 16 Mar 2024 06:27
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Contributors
Author:
David Grech
Author:
Antulio Tarazona
Author:
Maria Theresa De Leon
Author:
Jurgita Zekonyte
Author:
Harold M.H. Chong
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