Hepatocellular carcinoma: prospects for NK cell immunotherapy?
Hepatocellular carcinoma: prospects for NK cell immunotherapy?
Liver disease is a growing cause of death in the UK and the incidence of hepatocellular carcinoma (HCC) is rising (http://www.cancerresearchuk.org/). The combination of an immunosuppressive environment within the liver and suboptimal host anti-tumour immune responses may account for the poor survival outcome of HCC. Understanding how tumours evade immune recognition coupled with new insights into the unique immunological environment within the liver will be critical to developing liver-specific immunotherapies.
Kumar, Naveenta
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Khakoo, Salim
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273
Kumar, Naveenta
bc079422-0d86-4dc8-bf27-a5b180d2181d
Khakoo, Salim
6c16d2f5-ae80-4d9b-9100-6bfb34ad0273
Kumar, Naveenta and Khakoo, Salim
(2018)
Hepatocellular carcinoma: prospects for NK cell immunotherapy?
HLA.
(doi:10.1111/tan.13275).
Abstract
Liver disease is a growing cause of death in the UK and the incidence of hepatocellular carcinoma (HCC) is rising (http://www.cancerresearchuk.org/). The combination of an immunosuppressive environment within the liver and suboptimal host anti-tumour immune responses may account for the poor survival outcome of HCC. Understanding how tumours evade immune recognition coupled with new insights into the unique immunological environment within the liver will be critical to developing liver-specific immunotherapies.
Text
Kumar_et_al-2017-HLA
- Accepted Manuscript
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Accepted/In Press date: 12 April 2018
e-pub ahead of print date: 17 April 2018
Identifiers
Local EPrints ID: 420199
URI: http://eprints.soton.ac.uk/id/eprint/420199
ISSN: 2059-2310
PURE UUID: 3b6deeed-3d7c-46a0-bf8b-b38080584c4f
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Date deposited: 02 May 2018 16:30
Last modified: 16 Mar 2024 06:32
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Author:
Naveenta Kumar
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