European evidence-based guidelines on pancreatic cystic neoplasms
European evidence-based guidelines on pancreatic cystic neoplasms
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointestinal Endoscopy. It replaces the 2013 European consensus statement guidelines on PCN. European and non-European experts performed systematic reviews and used GRADE methodology to answer relevant clinical questions on nine topics (biomarkers, radiology, endoscopy, intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm, rare cysts, (neo)adjuvant treatment, and pathology). Recommendations include conservative management, relative and absolute indications for surgery. A conservative approach is recommended for asymptomatic MCN and IPMN measuring <40 mm without an enhancing nodule. Relative indications for surgery in IPMN include a main pancreatic duct (MPD) diameter between 5 and 9.9 mm or a cyst diameter ≥40 mm. Absolute indications for surgery in IPMN, due to the high-risk of malignant transformation, include jaundice, an enhancing mural nodule >5 mm, and MPD diameter >10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit for surgery. The European evidence-based guidelines on PCN aim to improve the diagnosis and management of PCN.
Journal Article
789-804
Abu Hilal, Mohammad
384e1c60-8519-4eed-8e92-91775aad4c47
European Study Group on Cystic Tumours of the Pancreas
May 2018
Abu Hilal, Mohammad
384e1c60-8519-4eed-8e92-91775aad4c47
European Study Group on Cystic Tumours of the Pancreas
(2018)
European evidence-based guidelines on pancreatic cystic neoplasms.
Gut, 67 (5), .
(doi:10.1136/gutjnl-2018-316027).
Abstract
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointestinal Endoscopy. It replaces the 2013 European consensus statement guidelines on PCN. European and non-European experts performed systematic reviews and used GRADE methodology to answer relevant clinical questions on nine topics (biomarkers, radiology, endoscopy, intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm, rare cysts, (neo)adjuvant treatment, and pathology). Recommendations include conservative management, relative and absolute indications for surgery. A conservative approach is recommended for asymptomatic MCN and IPMN measuring <40 mm without an enhancing nodule. Relative indications for surgery in IPMN include a main pancreatic duct (MPD) diameter between 5 and 9.9 mm or a cyst diameter ≥40 mm. Absolute indications for surgery in IPMN, due to the high-risk of malignant transformation, include jaundice, an enhancing mural nodule >5 mm, and MPD diameter >10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit for surgery. The European evidence-based guidelines on PCN aim to improve the diagnosis and management of PCN.
Text
789.full
- Version of Record
More information
Accepted/In Press date: 13 February 2018
e-pub ahead of print date: 24 March 2018
Published date: May 2018
Keywords:
Journal Article
Identifiers
Local EPrints ID: 420449
URI: http://eprints.soton.ac.uk/id/eprint/420449
ISSN: 1468-3288
PURE UUID: 7cfe433f-28eb-408e-a92a-8780fb43fc7c
Catalogue record
Date deposited: 08 May 2018 16:30
Last modified: 15 Mar 2024 19:46
Export record
Altmetrics
Contributors
Author:
Mohammad Abu Hilal
Corporate Author: European Study Group on Cystic Tumours of the Pancreas
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics