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Focal EEG slowing and chorea: electroclinical clues to the diagnosis of anti-NMDAR encephalitis

Focal EEG slowing and chorea: electroclinical clues to the diagnosis of anti-NMDAR encephalitis
Focal EEG slowing and chorea: electroclinical clues to the diagnosis of anti-NMDAR encephalitis

Variations in clinical presentation can lead to delays in the diagnosis and initiation of treatment of anti-N-methyl-D-aspartate receptor encephalitis. Most patients have an EEG study performed early in the course of their illness. Although not specific, there may be clues in the electroclinical features that should alert clinicians and electroencephalographers to the possibility of this diagnosis. This case is a reminder that anti- anti-N-methyl-D-aspartate receptor encephalitis may present initially with a movement disorder as the sole symptom, without features of an encephalopathy. In addition, it adds to the growing body of evidence that recognition of certain electroclinical clues may shorten the time to diagnosis. [Published with video sequence].

Acute Disease, Anti-N-Methyl-D-Aspartate Receptor Encephalitis, Child, Chorea, Diagnosis, Differential, Electrodiagnosis, Electroencephalography, Female, Humans, Case Reports, Journal Article
1294-9361
482-485
Osei-Lah, Abena
e6276a24-2d30-4a1f-8de2-d7cc5606965a
Durrant, Emma
f4bee40d-2d3d-47da-bc18-c89fef202a96
Hussain, Munir
dab14a25-bb8a-48e8-aed2-404f83557c19
Kirkham, Fenella
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58
Osei-Lah, Abena
e6276a24-2d30-4a1f-8de2-d7cc5606965a
Durrant, Emma
f4bee40d-2d3d-47da-bc18-c89fef202a96
Hussain, Munir
dab14a25-bb8a-48e8-aed2-404f83557c19
Kirkham, Fenella
1dfbc0d5-aebe-4439-9fb2-dac6503bcd58

Osei-Lah, Abena, Durrant, Emma, Hussain, Munir and Kirkham, Fenella (2014) Focal EEG slowing and chorea: electroclinical clues to the diagnosis of anti-NMDAR encephalitis. Epileptic Disorders, 16 (4), 482-485. (doi:10.1684/epd.2014.0708).

Record type: Article

Abstract

Variations in clinical presentation can lead to delays in the diagnosis and initiation of treatment of anti-N-methyl-D-aspartate receptor encephalitis. Most patients have an EEG study performed early in the course of their illness. Although not specific, there may be clues in the electroclinical features that should alert clinicians and electroencephalographers to the possibility of this diagnosis. This case is a reminder that anti- anti-N-methyl-D-aspartate receptor encephalitis may present initially with a movement disorder as the sole symptom, without features of an encephalopathy. In addition, it adds to the growing body of evidence that recognition of certain electroclinical clues may shorten the time to diagnosis. [Published with video sequence].

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More information

Published date: December 2014
Keywords: Acute Disease, Anti-N-Methyl-D-Aspartate Receptor Encephalitis, Child, Chorea, Diagnosis, Differential, Electrodiagnosis, Electroencephalography, Female, Humans, Case Reports, Journal Article

Identifiers

Local EPrints ID: 420599
URI: https://eprints.soton.ac.uk/id/eprint/420599
ISSN: 1294-9361
PURE UUID: 1931814a-c022-4716-8893-9bb4634163c7
ORCID for Fenella Kirkham: ORCID iD orcid.org/0000-0002-2443-7958

Catalogue record

Date deposited: 10 May 2018 16:31
Last modified: 13 Jun 2019 00:37

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