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Effects of an acaricide on asthmatic children with house dust mite allergy

Effects of an acaricide on asthmatic children with house dust mite allergy
Effects of an acaricide on asthmatic children with house dust mite allergy

D'Allergen is a recently available acaricidal and allergen reducing agent. To study any beneficial effects of treating houses with this agent in asthmatic children with dust mite allergy, histamine bronchial responsiveness was measured in 18 children before and 6–8 weeks after their homes were treated with the agent. Comparisons were with nine similar asthmatics whose homes were not treated. The mean provocative concentration of histamine causing a 20% fall in forced expiratory volume in 1s (PC20) increased from 1.02mg/L to 2.07mg/L in all 18 children who were studied (1.01 doubling doses). Bronchial responsiveness was relatively unchanged in a well matched control group of nine children studied over comparable time periods (PC20 pre was 1.25 mg/L, PC20 post was 0.67 mg/L). The results suggest that treating homes with D'Allergen reduces bronchial reactivity in asthmatic residents with house dust mite allergy. 1994 Japan Pediatric Society

acaricide, asthma, dust mite allergy
1328-8067
669-672
Quek, S.C.
d359ea40-f736-485a-abce-cd5ed6fdd18a
Chong, A.
167f9a69-e6b1-4e0d-aefa-4057a87dc9d3
Connett, G.J.
55d5676c-90d8-46bf-a508-62eded276516
Lee, B.W.
643a0988-a441-4752-a190-e1e392c98738
Quek, S.C.
d359ea40-f736-485a-abce-cd5ed6fdd18a
Chong, A.
167f9a69-e6b1-4e0d-aefa-4057a87dc9d3
Connett, G.J.
55d5676c-90d8-46bf-a508-62eded276516
Lee, B.W.
643a0988-a441-4752-a190-e1e392c98738

Quek, S.C., Chong, A., Connett, G.J. and Lee, B.W. (1994) Effects of an acaricide on asthmatic children with house dust mite allergy. Pediatrics International, 36 (6), 669-672. (doi:10.1111/j.1442-200X.1994.tb03267.x).

Record type: Article

Abstract

D'Allergen is a recently available acaricidal and allergen reducing agent. To study any beneficial effects of treating houses with this agent in asthmatic children with dust mite allergy, histamine bronchial responsiveness was measured in 18 children before and 6–8 weeks after their homes were treated with the agent. Comparisons were with nine similar asthmatics whose homes were not treated. The mean provocative concentration of histamine causing a 20% fall in forced expiratory volume in 1s (PC20) increased from 1.02mg/L to 2.07mg/L in all 18 children who were studied (1.01 doubling doses). Bronchial responsiveness was relatively unchanged in a well matched control group of nine children studied over comparable time periods (PC20 pre was 1.25 mg/L, PC20 post was 0.67 mg/L). The results suggest that treating homes with D'Allergen reduces bronchial reactivity in asthmatic residents with house dust mite allergy. 1994 Japan Pediatric Society

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Published date: December 1994
Keywords: acaricide, asthma, dust mite allergy

Identifiers

Local EPrints ID: 420682
URI: http://eprints.soton.ac.uk/id/eprint/420682
ISSN: 1328-8067
PURE UUID: 4d5733ff-7206-4ded-a98b-55c67dc030f6
ORCID for G.J. Connett: ORCID iD orcid.org/0000-0003-1310-3239

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Date deposited: 11 May 2018 16:30
Last modified: 16 Mar 2024 04:35

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Contributors

Author: S.C. Quek
Author: A. Chong
Author: G.J. Connett ORCID iD
Author: B.W. Lee

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