﻿Model of 10 parameters - stepwise BIC fit excluding parameters which were not statistically valid (and close to threshold)
modelling for log(1/EC50)

Response Log10(1/EC50)

Effect Summary
Source	LogWorth	                    	PValue
VE2_X	9.627	+++++++++++++++++++ 	0.00000
LOC	8.408	+++++++++++++++++   	0.00000
SpMax_B(p)	7.437	+++++++++++++++     	0.00000
DLS_04	7.069	++++++++++++++      	0.00000
VE2_H2	6.227	++++++++++++        	0.00000
RBF	4.402	+++++++++           	0.00004
P_VSA_MR_2	4.343	+++++++++           	0.00005
ChiA_Dz(i)	2.794	++++++              	0.00161
AVS_H2	2.734	+++++               	0.00185

Lack Of Fit
Source	DF	Sum of Squares	Mean Square	F Ratio
Lack Of Fit	74	25.050427	0.338519	1.1838
Pure Error	1	0.285957	0.285957		Prob > F
Total Error	75	25.336383		0.6390	
					Max RSq
				0.9964	

Summary of Fit
RSquare	0.68254
RSquare Adj	0.644445
Root Mean Square Error	0.581222
Mean of Response	0.497151
Observations (or Sum Wgts)	85

Analysis of Variance
Source	DF	Sum of Squares	Mean Square	F Ratio
Model	9	54.473237	6.05258	17.9167
Error	75	25.336383	0.33782		Prob > F
C. Total	84	79.809620		<.0001	

Parameter Estimates
Term	Estimate	Std Error	t Ratio	Prob>|t|
Intercept	46.06461	5.576028	8.26	<.0001
DLS_04	 -3.108799	0.523905	 -5.93	<.0001
LOC	1.0650309	0.159784	6.67	<.0001
VE2_X	 -42.95965	5.871957	 -7.32	<.0001
ChiA_Dz(i)	108.93231	33.27567	3.27	0.0016
SpMax_B(p)	 -4.921966	0.80202	 -6.14	<.0001
VE2_H2	 -32.54266	5.960536	 -5.46	<.0001
P_VSA_MR_2	 -0.005293	0.001222	 -4.33	<.0001
RBF	 -13.6496	3.124901	 -4.37	<.0001
AVS_H2	 -3.45211	1.069252	 -3.23	0.0018