﻿Model of 10 parameters - stepwise BIC fit excluding parameters from 10 parameter model which were highly correlated
modelling for log(1/EC50)

Response Log10(1/EC50)

Effect Summary
Source	LogWorth	                    	PValue
VE2_H2	4.264	+++++++++           	0.00005
SpMax_B(p)	3.519	+++++++             	0.00030
LOC	3.331	+++++++             	0.00047
P_VSA_MR_2	3.166	++++++              	0.00068
DLS_04	2.176	++++                	0.00666
RBF	1.316	+++                 	0.04829
AVS_H2	0.009	                    	0.97989

Lack Of Fit
Source	DF	Sum of Squares	Mean Square	F Ratio
Lack Of Fit	76	43.192375	0.568321	1.9874
Pure Error	1	0.285957	0.285957		Prob > F
Total Error	77	43.478331		0.5197	
					Max RSq
				0.9964	

Summary of Fit	
RSquare	0.455224
RSquare Adj	0.405699
Root Mean Square Error	0.751434
Mean of Response	0.497151
Observations (or Sum Wgts)	85

Analysis of Variance
Source	DF	Sum of Squares	Mean Square	F Ratio
Model	7	36.331289	5.19018	9.1918
Error	77	43.478331	0.56465		Prob > F
C. Total	84	79.809620		<.0001	

Parameter Estimates
Term	Estimate	Std Error	t Ratio	Prob>|t|
Intercept	20.801964	5.662764	3.67	0.0004
DLS_04	 -1.740188	0.623973	 -2.79	0.0067
LOC	0.6680613	0.182752	3.66	0.0005
SpMax_B(p)	 -3.707496	0.979485	 -3.79	0.0003
VE2_H2	 -30.32721	7.095854	 -4.27	<.0001
P_VSA_MR_2	 -0.00544	0.001537	 -3.54	0.0007
RBF	 -7.506734	3.740717	 -2.01	0.0483
AVS_H2	0.0307784	1.216822	0.03	0.9799