Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability
Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability
The influence of the degree of residual stenosis (DOR) on the hemodynamics inside coronary arteries is investigated through three-dimensional (3D) numerical simulations. The vascular wall permeability is investigated and the effect of the non-Newtonian viscosity discussed. The results agree in predicting an abrupt increase in wall permeability above 45% DOR, indicating that the implant could lead to a massive restenosis. This behavior is considered to be due to the shift of the regions involved by low and oscillatory wall shear stress (WSS), from the zone adjacent to the struts toward the center of the stent meshes.
653-665
Boghi, Andrea
54a72da6-c8a2-468c-9773-897efac0638f
Di Venuta, Ivan
c478ec72-9e42-45cd-9afb-147f93b6835b
Gori, Fabio
f7e76614-37d8-4c3b-b7b0-8c6603a4515f
2017
Boghi, Andrea
54a72da6-c8a2-468c-9773-897efac0638f
Di Venuta, Ivan
c478ec72-9e42-45cd-9afb-147f93b6835b
Gori, Fabio
f7e76614-37d8-4c3b-b7b0-8c6603a4515f
Boghi, Andrea, Di Venuta, Ivan and Gori, Fabio
(2017)
Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability.
Numerical Heat Transfer; Part A: Applications, 71 (6), .
(doi:10.1080/10407782.2017.1293976).
Abstract
The influence of the degree of residual stenosis (DOR) on the hemodynamics inside coronary arteries is investigated through three-dimensional (3D) numerical simulations. The vascular wall permeability is investigated and the effect of the non-Newtonian viscosity discussed. The results agree in predicting an abrupt increase in wall permeability above 45% DOR, indicating that the implant could lead to a massive restenosis. This behavior is considered to be due to the shift of the regions involved by low and oscillatory wall shear stress (WSS), from the zone adjacent to the struts toward the center of the stent meshes.
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Accepted/In Press date: 20 January 2017
e-pub ahead of print date: 27 March 2017
Published date: 2017
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Local EPrints ID: 421759
URI: http://eprints.soton.ac.uk/id/eprint/421759
ISSN: 1040-7782
PURE UUID: cdb7742d-ce2e-4ce9-afd7-29102f620b66
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Date deposited: 26 Jun 2018 16:30
Last modified: 15 Mar 2024 20:21
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Author:
Ivan Di Venuta
Author:
Fabio Gori
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