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Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability

Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability
Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability

The influence of the degree of residual stenosis (DOR) on the hemodynamics inside coronary arteries is investigated through three-dimensional (3D) numerical simulations. The vascular wall permeability is investigated and the effect of the non-Newtonian viscosity discussed. The results agree in predicting an abrupt increase in wall permeability above 45% DOR, indicating that the implant could lead to a massive restenosis. This behavior is considered to be due to the shift of the regions involved by low and oscillatory wall shear stress (WSS), from the zone adjacent to the struts toward the center of the stent meshes.

1040-7782
653-665
Boghi, Andrea
54a72da6-c8a2-468c-9773-897efac0638f
Di Venuta, Ivan
c478ec72-9e42-45cd-9afb-147f93b6835b
Gori, Fabio
f7e76614-37d8-4c3b-b7b0-8c6603a4515f
Boghi, Andrea
54a72da6-c8a2-468c-9773-897efac0638f
Di Venuta, Ivan
c478ec72-9e42-45cd-9afb-147f93b6835b
Gori, Fabio
f7e76614-37d8-4c3b-b7b0-8c6603a4515f

Boghi, Andrea, Di Venuta, Ivan and Gori, Fabio (2017) Three-dimensional numerical simulation of a failed coronary stent implant at different degrees of residual stenosis. Part II: apparent viscosity and wall permeability. Numerical Heat Transfer Part A: Applications, 71 (6), 653-665. (doi:10.1080/10407782.2017.1293976).

Record type: Article

Abstract

The influence of the degree of residual stenosis (DOR) on the hemodynamics inside coronary arteries is investigated through three-dimensional (3D) numerical simulations. The vascular wall permeability is investigated and the effect of the non-Newtonian viscosity discussed. The results agree in predicting an abrupt increase in wall permeability above 45% DOR, indicating that the implant could lead to a massive restenosis. This behavior is considered to be due to the shift of the regions involved by low and oscillatory wall shear stress (WSS), from the zone adjacent to the struts toward the center of the stent meshes.

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More information

Accepted/In Press date: 20 January 2017
e-pub ahead of print date: 27 March 2017
Published date: 2017

Identifiers

Local EPrints ID: 421759
URI: https://eprints.soton.ac.uk/id/eprint/421759
ISSN: 1040-7782
PURE UUID: cdb7742d-ce2e-4ce9-afd7-29102f620b66
ORCID for Andrea Boghi: ORCID iD orcid.org/0000-0002-9387-326X

Catalogue record

Date deposited: 26 Jun 2018 16:30
Last modified: 07 Aug 2019 00:58

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