The University of Southampton
University of Southampton Institutional Repository

Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system

Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system
Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system
The human resting muscle tone (HRMT) system provides structural and functional support to skeletal muscle and associated myofascial structures (tendons, fascia) in normal life. Little information is available on changes to the HRMT in bed rest. A set of dynamic oscillation mechanosignals ([Hz], [N/m], log decrement, [ms]) collected and computed by a hand-held digital palpation device (MyotonPRO) were used to study changes in tone and in key biomechanical and viscoelastic properties in global and postural skeletal muscle tendons and fascia from a non-exercise control (CTR) and an exercise (JUMP) group performing reactive jumps on a customized sledge system during a 60 days head-down tilt bed rest (RSL Study 2015–2016). A set of baseline and differential natural oscillation signal patterns were identified as key determinants in resting muscle and myofascial structures from back, thigh, calf, patellar and Achilles tendon, and plantar fascia. The greatest changes were found in thigh and calf muscle and tendon, with little change in the shoulder muscles. Functional tests (one leg jumps, electromyography) showed only trends in relevant leg muscle groups. Increased anti-Collagen-I immunoreactivity found in CTR soleus biopsy cryosections was absent from JUMP. Results allow for a muscle health status definition after chronic disuse in bed rest without and with countermeasure, and following reconditioning. Findings improve our understanding of structural and functional responses of the HRMT to disuse and exercise, may help to guide treatment in various clinical settings (e.g., muscle tone disorders, neuro-rehabilitation), and promote monitoring of muscle health and training status in personalized sport and space medicine.
1664-042X
Schoenrock, Britt
dd80f17a-fe70-43f7-b8a8-123c0eb280a3
Zander, Vanja
052f9962-9daf-45b1-9a26-31d58d1245a0
Dern, Sebastian
8fb6714d-508a-4dc3-b560-7725c9ff02a6
Limper, Ulrich
25859dfd-c01d-4445-a43a-c0a6a7a67c8e
Mulder, Edwin
1a27bfe8-7fcb-46d2-b214-32613bbffa18
Veraksitš, Alar
7198ecd5-32dc-4f0e-bb42-77599a4a4f42
Viir, Ragnar
9f6b15b3-92f4-40d6-90e5-b8266d519913
Krämer, Andreas
5f9467a5-fcc1-4d05-b03d-67467599ee0e
Stokes, Maria
71730503-70ce-4e67-b7ea-a3e54579717f
Salanova, Michele
97cd5565-1dd6-49fc-bd06-96ea9a233e5d
Peipsi, Aleko
6b43ba06-7563-4be7-87bf-54769e41ab87
Blottner, Dieter
71a977aa-34ad-4462-b866-dad0ab73981c
Schoenrock, Britt
dd80f17a-fe70-43f7-b8a8-123c0eb280a3
Zander, Vanja
052f9962-9daf-45b1-9a26-31d58d1245a0
Dern, Sebastian
8fb6714d-508a-4dc3-b560-7725c9ff02a6
Limper, Ulrich
25859dfd-c01d-4445-a43a-c0a6a7a67c8e
Mulder, Edwin
1a27bfe8-7fcb-46d2-b214-32613bbffa18
Veraksitš, Alar
7198ecd5-32dc-4f0e-bb42-77599a4a4f42
Viir, Ragnar
9f6b15b3-92f4-40d6-90e5-b8266d519913
Krämer, Andreas
5f9467a5-fcc1-4d05-b03d-67467599ee0e
Stokes, Maria
71730503-70ce-4e67-b7ea-a3e54579717f
Salanova, Michele
97cd5565-1dd6-49fc-bd06-96ea9a233e5d
Peipsi, Aleko
6b43ba06-7563-4be7-87bf-54769e41ab87
Blottner, Dieter
71a977aa-34ad-4462-b866-dad0ab73981c

Schoenrock, Britt, Zander, Vanja, Dern, Sebastian, Limper, Ulrich, Mulder, Edwin, Veraksitš, Alar, Viir, Ragnar, Krämer, Andreas, Stokes, Maria, Salanova, Michele, Peipsi, Aleko and Blottner, Dieter (2018) Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system. Frontiers in Physiology, 9, [810]. (doi:10.3389/fphys.2018.00810).

Record type: Article

Abstract

The human resting muscle tone (HRMT) system provides structural and functional support to skeletal muscle and associated myofascial structures (tendons, fascia) in normal life. Little information is available on changes to the HRMT in bed rest. A set of dynamic oscillation mechanosignals ([Hz], [N/m], log decrement, [ms]) collected and computed by a hand-held digital palpation device (MyotonPRO) were used to study changes in tone and in key biomechanical and viscoelastic properties in global and postural skeletal muscle tendons and fascia from a non-exercise control (CTR) and an exercise (JUMP) group performing reactive jumps on a customized sledge system during a 60 days head-down tilt bed rest (RSL Study 2015–2016). A set of baseline and differential natural oscillation signal patterns were identified as key determinants in resting muscle and myofascial structures from back, thigh, calf, patellar and Achilles tendon, and plantar fascia. The greatest changes were found in thigh and calf muscle and tendon, with little change in the shoulder muscles. Functional tests (one leg jumps, electromyography) showed only trends in relevant leg muscle groups. Increased anti-Collagen-I immunoreactivity found in CTR soleus biopsy cryosections was absent from JUMP. Results allow for a muscle health status definition after chronic disuse in bed rest without and with countermeasure, and following reconditioning. Findings improve our understanding of structural and functional responses of the HRMT to disuse and exercise, may help to guide treatment in various clinical settings (e.g., muscle tone disorders, neuro-rehabilitation), and promote monitoring of muscle health and training status in personalized sport and space medicine.

Text
Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system - Accepted Manuscript
Restricted to Registered users only
Download (1MB)
Request a copy
Text
Bed rest, exercise countermeasure and reconditioning effects on the human resting muscle tone system - Version of Record
Available under License Creative Commons Attribution.
Download (4MB)

More information

Accepted/In Press date: 8 June 2018
e-pub ahead of print date: 3 July 2018

Identifiers

Local EPrints ID: 422460
URI: http://eprints.soton.ac.uk/id/eprint/422460
ISSN: 1664-042X
PURE UUID: 210d0b5f-10b5-4216-98f4-b0d94f7491de
ORCID for Maria Stokes: ORCID iD orcid.org/0000-0002-4204-0890

Catalogue record

Date deposited: 24 Jul 2018 16:30
Last modified: 07 Oct 2020 01:48

Export record

Altmetrics

Contributors

Author: Britt Schoenrock
Author: Vanja Zander
Author: Sebastian Dern
Author: Ulrich Limper
Author: Edwin Mulder
Author: Alar Veraksitš
Author: Ragnar Viir
Author: Andreas Krämer
Author: Maria Stokes ORCID iD
Author: Michele Salanova
Author: Aleko Peipsi
Author: Dieter Blottner

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×